Pharmacology XII

Alpha or beta-adrenergic blocking drugs act by

A mechanism for the antiadrenergic action of guanethidine is

Which of the following statements most accurately describes the effectiveness of action of methyldopa?

The mechanism of action of reserpine is to

Amphetamine acts by

Which of the following characterizes the mechanism of action on levodopa?

Which of the following combinations of agents would be necessary to block the cardiovascular effects produced by the injection of a sympathomimetic drug?

Which of the following drugs competitively blocks the action of norepinephrine at beta-adrenergic receptors?

Pretreatment with reserpine prevents a response to which of the following agents?

Each of the following drugs is considered to be a direct-acting catecholamine EXCEPT

After pretreatment with phentolamine, intravenous administration of epinephrine should result in a. Relaxation of bronchial smooth muscle b. Positive chronotropic and inotropic effects c. Splanchnic vasoconstriction d. Dilation of skeletal muscle vascular beds e. Secretion of a mucoid viscous saliva

Which of the following changes produced by intravenous administration of epinephrine result from stimulation of betaadrenergic receptors? a. Respiratory inhibition b. Cardiac acceleration c. Dilation of the pupil d. Increased systolic pressure e. Decreased diastolic pressure

Which of the following is NOT an action of epinephrine when administered intravenously in a high dose?

“Epinephrine reversal” of blood pressure can best be demonstrated by injecting epinephrine intravenously after pretreatment with

Each of the following is a predictable adverse effect of drugs that block the sympathetic nervous system EXCEPT

Injection of a pressor dose of norepinephrine may result in a decreased heart rate because of

Alpha-adrenergic agonists are used in combination with local anesthetics to a. Stimulate myocardial contraction b. Reduce vascular absorption of the local anesthetic c. Increase the rate of liver metabolism of the local anesthetic d. Increase the concentration of the local anesthetic at its receptor site e. Antagonize the vasodilating effects of the local anesthetic

Administration of an otherwise effective pressor dose of epinephrine could cause an “epinephrine reversal” in a patient taking which of the following drugs?

Of the following sympathomimetic agents, the most potent bronchodilator is

Administration of which of the following drugs would produce vasoconstriction of the gingival vessels? a. Levonordefrin b. Phentolamine c. Epinephrine d. Propranolol e. Phenylephrine

Carbidopa, a dopa-decarboxylase inhibitor, is often used in the treatment of parkinsonism because it

Of the following, one of the most effective treatments currently available in the U.S. for most patients suffering from parkinsonism involves oral administration of

Levodopa therapy for Parkinson disease may result in each of the following effects EXCEPT:

Adverse effects of levodopa include: a. Arrhythmias b. Psychotic disturbances c. Nausea and vomiting d. Abnormal involuntary movements

Which of the following drugs would be most likely taken by an asthmatic patient?