Question 1
Question
Occurrence of which of the following is LEAST characteristic of narcotic ingestion?
Question 2
Question
Therapeutic doses of morphine administered intramuscularly may produce
a. Constipation
b. Euphoria
c. Dysphoria
d. Mental clouding
e. Decreased response to pain
Answer
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A) (a) and (b) only
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B) (a), (b) and (d)
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C) (a), (d) and (e)
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D) (c), (d) and (e)
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E) All of the above
Question 3
Question
Which of the following are pharmacologic effects of morphine?
a. Respiratory depression
b. Euphoria
c. Sedation
d. Constipation
e. Dysphoria
Answer
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A) (a), (b) and (c)
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B) (a), (b) and (d)
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C) (a) and (e)
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D) (c), (d) and (e)
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E) All of the above
Question 4
Question
Which of the following drugs acts to suppress the cough reflex?
Answer
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A) ASA
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B) Codeine
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C) Meperidine
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D) Acetaminophen
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E) Phenyibutazone
Question 5
Question
Morphine binds to which site to produce analgesia?
Answer
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A) By binding to specific receptors in the CNS
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B) By decreasing the influx of sodium
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C) By decreasing the synthesis of prostaglandins
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D) By decreasing nerve activatin at the site of injury
Question 6
Question
Morphine causes vomiting by
Answer
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A) A direct irritant action on the gastric mucosa
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B) Stimulation of the nodose ganglion of the vagus nerve
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C) Stimulation of the medullary chemoreceptor trigger zone
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D) Direct stimulation of the gastrointestinal musculature
Question 7
Question
The decrease in ventilation caused by morphine, meperidine and some of the related opioids depends chiefly upon
Answer
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A) Depression of cortical activity
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B) Peripheral blockade of chemoreceptor impulses
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C) An increase in carbon dioxide concentration in the blood
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D) Blockade of afferent autonomic impulses from the lungs
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E) Loss of sensitivity of the medullary respiratory center to carbon dioxide
Question 8
Question
Small doses of barbiturates and morphine depress respiration primarily by
Answer
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A) A parasympathominetic action
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B) Inhibiting the Herine-Bueuer reflex
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C) Rendering the aortic chemoreceptor system insensitive to O2
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D) Rendering the respiratory center in the brain stem less sensitive to changes in CO2
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E) A specific effect at myoneural junctions of phrenic and intercostal nerves
Question 9
Question
Which of the following are pathognomonic symptoms of narcotic overdose?
Answer
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A) Miosis, coma and depressed respiration
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B) Mydriasis, coma and smooth muscle spasms
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C) Mydriasis, coma and depressed respiration
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D) Miosis, convulsions and depressed respiration
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E) Mydriasis, convulsions and depressed respiration
Question 10
Question
The cause of death with opioid intoxication is
Question 11
Question
Which of the following is an opioid that has both agonistic and antagonistic activities?
Answer
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A) Codeine
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B) Methadone
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C) Naloxone
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D) Meperidine
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E) Pentazocine
Question 12
Question
A heroin-dependent patient should NOT be given nalbuphine (Nubain) for pain because
Answer
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A) It has no analgesic properties
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B) It may produce respiratory depression
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C) As a mixed agonist-antagonist, it can elicit withdrawal symptoms
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D) The high abuse potential of nalbuphine may add to the patient's problems
Question 13
Question
A patient while not currently taking drugs has a history (6 months ago) of narcotic dependency. Which of the following analgesics should be avoided in this patient?
Answer
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A) Aspirin
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B) Pentazcine
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C) propoxyphene
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D) Indomethacin
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E) Acetaminophen
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F) None of the above
Question 14
Question
Which of the following statements does NOT characterize pentazocine?
Answer
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A) It is equianalgesic with codeine
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B) It is a partial opioid antagonist
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C) Its abuse potential is less than that of heroin
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D) It may induce dysphoria and mental aberrations
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E) It is effective only on parenteral administration
Question 15
Question
The antagonist of choice in the treatment of opioid overdosage is
Answer
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A) Naloxone
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B) Nalorphine
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C) Pentazocine
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D) Levallorphan
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E) Propoxyphene
Question 16
Question
Which of the following is a complete antagonist of the opioid receptor and the agent of choice in the treatment of narcotic overdose?
Answer
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A) Naloxone
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B) Nalorphine
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C) Cyclazocine
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D) Levallorphan
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E) None of the above
Question 17
Question
Methadone is used in detoxification (drug withdrawal) of patients physically dependent on morphine because methadone
Answer
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A) Precipitates withdrawal reactions
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B) Antagonizes the depressant actions of morphine
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C) Will not in itself produce physical dependence
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D) Withdrawal reactions are less intense and stressful than those of morphine
Question 18
Question
Which of the following drugs is currently widely used in treating opioid-dependent individuals?
Answer
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A) Codeine
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B) Methadone
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C) Alphaprodine
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D) Pentazocine
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E) Meperidine
Question 19
Question
Meperidine (Demerol) is