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Pharmacology IX

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Praxis Tests: Pharmacology Quiz on Pharmacology IX, created by ACAPUN INSTITUTE on 08/11/2021.
ACAPUN INSTITUTE
Quiz by ACAPUN INSTITUTE, updated more than 1 year ago
ACAPUN INSTITUTE
Created by ACAPUN INSTITUTE about 3 years ago
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Resource summary

Question 1

Question
Which of the following are pharmacologic properties of antipsychotic drugs? a. They block the dopamine receptor b. They affect the hypothalamic temperature regulation system c. They cause emesis d. They are synergistic with LSD e. They cause hypertension
Answer
  • a) (a) and (b) only
  • b) (a), (b) and (c)
  • c) (b), (c) and (d)
  • d) (c), (d) and (e)
  • e) (d) and (e) only

Question 2

Question
The antipsychotic effects of the phenothiazines are probably the result of
Answer
  • a. Release of serotonin in the brain
  • b. Release of norepinephrine in the brain
  • c. Blockade of dopaminergic sites in the brain
  • d. Prevention of the release of norepinephrine from brain neuron terminals
  • e. Increase in the dopamine content of the cerebral cortex

Question 3

Question
The antipsychotic effects of phenothiazines result from
Answer
  • a. Release of serotonin in the brain
  • b. Release of norepinephrine in the brain
  • c. Blockade of dopaminergic sites in the brain
  • d. An increase in the dopamine content of the cerebral cortex
  • e. Prevention of the release of norepinephrine from brain neuron terminals

Question 4

Question
Chlorpromazine and related drugs are thought at act by blocking which of the following receptors?
Answer
  • a. Adrenergic
  • b. Muscarinic
  • c. Dopaminergic
  • d. Central serotonin

Question 5

Question
Which of the following is an irreversible side-effect resulting from longterm administration of phenothiazines?
Answer
  • a. Sedation
  • b. Xerostomia
  • c. Infertility
  • d. Parkinsonism
  • e. Tardive dyskinesia

Question 6

Question
Tardive dyskinesia is a neurological side-effect of which of the following classes of drugs?
Answer
  • a. Alcohols
  • b. Tricyclic antidepressants
  • c. Barbiturate antiepileptics
  • d. Phenothiazine antipsychotics
  • e. Monoamine oxidase inhibitors

Question 7

Question
Which of the following drugs are most likely to cause extrapyramidal\ stimulation?
Answer
  • a. Antibiotics
  • b. Salicylates
  • c. Barbiturates
  • d. Phenothiazines
  • e. Benzodiazepines

Question 8

Question
Phenothiazine derivatives do NOT produce
Answer
  • a. Jaundice
  • b. Xerostomia
  • c. Gingival hyperplasia
  • d. Postural hypotension
  • e. Symptoms of parkinsonism

Question 9

Question
All of the following actions are associated with the use of chlorpromazine EXCEPT:
Answer
  • a. Jaundice
  • b. Photosensitivity
  • c. Excessive salivation
  • d. Anticholinergic effects
  • e. Antiadrenergic effects

Question 10

Question
The drug most commonly used to treat severe mental depression is
Answer
  • a. Sodium
  • b. Imipramine
  • c. Chlorpromazine
  • d. Tranylcypromine
  • e. Dextroamphetamine

Question 11

Question
Which of the following drugs is most effective as an antidepressant?
Answer
  • a. Diazepam
  • b. Reserpine
  • c. Amitriptyline
  • d. Chlorpromazine
  • e. Hydroxyzine

Question 12

Question
Which of the following is most likely to be the major mechanism of action of the tricyclic antidepressants?
Answer
  • a. Enhanced release of acetylcholine
  • b. Inhibition of neuronal synthesis of norepinephrine
  • c. Potentiation of serotonin synthesis in nervous tissue
  • d. Stimulation of reuptake of norepinephrine from the synaptic cleft
  • e. Blockade of the reuptake of amine neurotransmitters released into the synaptic cleft

Question 13

Question
Tricyclic antidepressants have a prominent side effect that most nearly resembles the usual pharmacological action of
Answer
  • a. Codeine
  • b. Atropine
  • c. Ephedrine
  • d. Propranolol
  • e. Methacholine

Question 14

Question
Which of the following drugs has its primary use in the treatment of the manic phase of depressive psychosis?
Answer
  • a. Lithium
  • b. Reserpine
  • c. Imipramine
  • d. Amphetamine
  • e. Chlorpromazine

Question 15

Question
Which of the following are pharmacologic properties of antipsychotic drugs? a. They block the dopamine receptor b. They affect the hypothalamic temperature regulation system c. They cause emesis d. They are synergistic with LSD e. They cause hypertension
Answer
  • a) (a) and (b) only
  • b) (a), (b) and (c)
  • c) (b), (c) and (d)
  • d) (c), (d) and (e)
  • e) (d) and (e) only

Question 16

Question
The antipsychotic effects of the phenothiazines are probably the result of
Answer
  • a. Release of serotonin in the brain
  • b. Release of norepinephrine in the brain
  • c. Blockade of dopaminergic sites in the brain
  • d. Prevention of the release of norepinephrine from brain neuron terminals
  • e. Increase in the dopamine content of the cerebral cortex

Question 17

Question
The antipsychotic effects of phenothiazines result from
Answer
  • a. Release of serotonin in the brain
  • b. Release of norepinephrine in the brain
  • c. Blockade of dopaminergic sites in the brain
  • d. An increase in the dopamine content of the cerebral cortex
  • e. Prevention of the release of norepinephrine from brain neuron terminals

Question 18

Question
Chlorpromazine and related drugs are thought at act by blocking which of the following receptors?
Answer
  • a. Adrenergic
  • b. Muscarinic
  • c. Dopaminergic
  • d. Central serotonin

Question 19

Question
Which of the following is an irreversible side-effect resulting from longterm administration of phenothiazines?
Answer
  • a. Sedation
  • b. Xerostomia
  • c. Infertility
  • d. Parkinsonism
  • e. Tardive dyskinesia

Question 20

Question
Tardive dyskinesia is a neurological side-effect of which of the following classes of drugs?
Answer
  • a. Alcohols
  • b. Tricyclic antidepressants
  • c. Barbiturate antiepileptics
  • d. Phenothiazine antipsychotics
  • e. Monoamine oxidase inhibitors

Question 21

Question
Which of the following drugs are most likely to cause extrapyramidal\ stimulation?
Answer
  • a. Antibiotics
  • b. Salicylates
  • c. Barbiturates
  • d. Phenothiazines
  • e. Benzodiazepines

Question 22

Question
Phenothiazine derivatives do NOT produce
Answer
  • a. Jaundice
  • b. Xerostomia
  • c. Gingival hyperplasia
  • d. Postural hypotension
  • e. Symptoms of parkinsonism

Question 23

Question
All of the following actions are associated with the use of chlorpromazine EXCEPT:
Answer
  • a. Jaundice
  • b. Photosensitivity
  • c. Excessive salivation
  • d. Anticholinergic effects
  • e. Antiadrenergic effects

Question 24

Question
The drug most commonly used to treat severe mental depression is
Answer
  • a. Sodium
  • b. Imipramine
  • c. Chlorpromazine
  • d. Tranylcypromine
  • e. Dextroamphetamine

Question 25

Question
Which of the following drugs is most effective as an antidepressant?
Answer
  • a. Diazepam
  • b. Reserpine
  • c. Amitriptyline
  • d. Chlorpromazine
  • e. Hydroxyzine

Question 26

Question
Which of the following is most likely to be the major mechanism of action of the tricyclic antidepressants?
Answer
  • a. Enhanced release of acetylcholine
  • b. Inhibition of neuronal synthesis of norepinephrine
  • c. Potentiation of serotonin synthesis in nervous tissue
  • d. Stimulation of reuptake of norepinephrine from the synaptic cleft
  • e. Blockade of the reuptake of amine neurotransmitters released into the synaptic cleft

Question 27

Question
Tricyclic antidepressants have a prominent side effect that most nearly resembles the usual pharmacological action of
Answer
  • a. Codeine
  • b. Atropine
  • c. Ephedrine
  • d. Propranolol
  • e. Methacholine

Question 28

Question
Which of the following drugs has its primary use in the treatment of the manic phase of depressive psychosis?
Answer
  • a. Lithium
  • b. Reserpine
  • c. Imipramine
  • d. Amphetamine
  • e. Chlorpromazine

Question 29

Question
Lithium carbonate is particularly effective in treating
Answer
  • a. Parkinsonism
  • b. Hypertension
  • c. Schizophrenia
  • d. Acute anxiety
  • e. Manic-depressive psychosis

Question 30

Question
The current drug of choice for treatment of the manic phase of manic-depressive psychosis is
Answer
  • a. Lithium
  • b. Caffeine
  • c. Reserpine
  • d. Imipramine
  • e. Amphetamine
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