Zusammenfassung der Ressource
Epithelial Transport
- Transporters set up multiple gradients which drive paracellular and transcellular movement
- Oncotic, Chemical and Voltage gradients
- Epithelia cells isolate the internal environment from the external environment and regulate the movement of solutes and water to and from the body
- 2 Types of epithelia: absorptive and secretive
- The assymetrical distribution of carriers in the seperate membranes of the cells allows vectorial transport to take place
- Tight junctions seperate the basolateral and apical membrane of the cell, hold the cells together and reflect solutes and water
- TIGHT: prevent significant movement of molecules between cells, high transepithelial potential difference, can withstand high osmotic gradients and found distally
- LEAKY: prlow transepithelial potential difference