Zusammenfassung der Ressource
Obstetric Cholostasis
- Signs and Symptoms
- Dark Urine & Pale Stools
- Caused by absence of bile that contributes to the usual colour
- Abnormal Liver Function Tests
- AST, ALT, GGT, Alkaline Phosphate
- caused by the condition being a liver disorder
- Mild Jaundice
- caused by build up of bilirubin levels
- Can lead to vit k deficiency
- Tiredness
- Can lead to depression
- Persistent Pruitus (Rash)
- Caused by raised levels of bile acids
- Sickness & Poor Apitite
- Caused by increased bile acid levels
- UTI's
- caused by build up of liver enzymes
- Underlying cause not known, but may have genetic and environmental factors
- Liver Disorder
- Implications
- Maternal
- Stress
- Psycological and Physical
- Caused by intense itching, lack of sleep and fetal concerns
- Information avaialable from the British Liver trust
- Gallstones
- Caused by imbalance of bile make up causing Cholestrol levels to become too high and form stones
- Malabsorbtion of Vit K
- 10mg daily from 32wks
- PPH - increased risk by upto 25%
- fetal monitoring req: due to fetal distress risk
- Sleep Deprevation
- caused by itching
- Fetal
- Spontaneous Pre-term birth
- Mec stained liquor
- Risk of Fetal aspiration
- Iatrogenic pre-term birth
- Sudden IUD/Stillbirth
- Fetal Distress
- Bile Acids can cross the placenta
- can cause 02 deprevation to the fetus due to malfunction