Zusammenfassung der Ressource
Lecture (1)
- Levels of structural complexity
- 1- chemical level
2- cellular level
3- tissue level
4- organ level
5- system level
6- organismal level
- The shape of a cell serves its function
- For example :
- sperm cell
- smooth muscle cell
- nerve cell
- RBC
- Epithelial cell
- Cell-cell communication
- Cell (1) : send signal in a shape of hormone.
Cell (2) :
a- receive the signal via receptors on the plasma membrane.
b- send it inside.
c- translate it via biochemical machinery.
- Typical structure of a cell
- The Nucleus
- -
- The cytoplasm
- Organelles
- Endoplasmic Reticulum
- Rough ER
- - Ribosomes-attached (Protein synthesis) and ER for processing and sorting .
- synthesize phospholipids .
- Smooth ER
- - Extend from rough ER.
- synthesize fatty acids and steroids.
- contain enzymes that detoxify drugs.
- store Ca ion that triggers contraction in muscle cells .
- Mitochondria
- - The power house.
- Has its own DNA (from mother )
- Golgi complex
- Proteins are :
1- Modified.
2- Sorted.
3- Packed.
- Ribosomes
- Protein synthesis
1- free (used in cytosol).
2- attached to ER (secretion outside the cell).
- Lysosomes
- - Form from Golgi complex.
- Hydrolytic enzymes.
- Carry out :
1- autophagy.
2- autolysis.
3- extracellular digestion.
- The cytosol
- - 55% of cell volume.
- site of chemical reaction.
- contains dissolved particles .
- The cell membrane
- Introduction
- Arrangement of membrane proteins
(Structurally)
- Integral
Proteins
- Peripheral
Proteins
- Functions of membrane proteins
(Functionally)
- 1- Ion channel
(Integral)
2- Carrier/Transporters
(Integral)
3- Receptor (Integral)
4- Enzyme
(Integral and peripheral)
5- Linker (Integral and peripheral)
6- Cell identity marker (glycoprotein)
- The cytoskeleton
- The Microfilaments
- Intermediate filaments
- The Microtubules
- Cell junction
- e- Hemidesmosomes
- d- Desmosomes
- c- Adherens junction
- b- Gap junction
- a- Tight junction
- Cellular communication