Zusammenfassung der Ressource
Seizure
- Diagnostics
- Electroencephalogram
(EEG)- 24hrs
Anmerkungen:
- may not have EEG abonoral
- Comprehensive assessment
- Magnetoencephalography (greater sensitivity)
- CBC, metabolic chemistry
- Liver, kidney function , UA
- CT or MRI r/o structural Lesion
- Cerebral angiography, PET scan, MRA
- Clinical
Manifestations
- Generalized
- Tonic clonic
Anmerkungen:
- Tonic 10-20s, clonic 30-40s, excessive salivation, tongue/cheek biting, Cyanosis- "fall to ground"
* post ictal - muscle soreness, fatigue, pt. may sleep for hours, may not feel normal for hours or days, Nop memory of seizure
- Preceded by aura!- this
is generalized
secondarily
- Second generalized- Todd's
Paralysis (focal weakness)
- clonic Seizure
Anmerkungen:
- begin with loss of consciouness and sudden loss of muscle tone, limb jerking, hyperventilation, eye roll back, froth at mouth
- Atonic
- Sudden loss of muscle tone,
consciousness returns by the
time they hit the ground
- Myclonic
Anmerkungen:
- forceful enough to cause fall
- Excessive jerking
- Tonic
Anmerkungen:
- sudden increase tone, incontinence, breathing cessation, cyanosis, fixed dilated pupils, fall
- Absence Seizure
- Typical
Anmerkungen:
- children rarely beyond adolescent, cease with maturity or develope into another type, percipitation of flashlights & hyperventilation
- Staring spells
"daydreaming"
- percipitated by
hyperventilation &
lights
- 3hz per second EEG
spike & wave
pattern
- often unnoticed, may
be 100x a day, eyelid
fluttering,
automatisms
- Atypical
- Staring spells
with other
S&S
- Brief warning
- Peculiar behavior durning
- EEG greater or less than
3Hz spike & wave pattern
- confusion after
- Longer lasting &
loss of postural
tone
- Focal
- Complex
Anmerkungen:
- Display strange behaviors, Lip smacking, automatisms- repetitive movement, retrograde amnesia- not daydreaming that is how you differentiate
- Simple
Anmerkungen:
- sudden and unexplaibable feelings, may hear,taste, feel or see things that are not real, psychic symptoms, recurrent muscle contractions, abnormal sensation of hallucinations, Tachycardia, flushing hypotension/hypertension
- psychogenic
Anmerkungen:
- Pseudoseizure, Use video EEG
- Febrile
Anmerkungen:
- Antipyretics
Anmerkungen:
- NO tepid Baths
- Protect from injury
- rectal diazepam/diazempam gel (second seizure likely)
- Phases of
seizure
Anmerkungen:
- (1) Prodromal - signs precede seizure
(2) aural- sensory warning
(3) Ictal- active
(4) postictal- recovery after seizure (muscle aches, headache, confusion)
- Interventions
- Pharmacotherapy
- Absence & Myoclonic
Anmerkungen:
- ethosuzimide, divaleproex, clonazepam ,
- Tonic clonic & focal
Anmerkungen:
- phenytoin- peeling rash, Hyperplasia of gums, hirutism in young adults common. carbamezapine, phenobarbitol, divalproex, primid
- Broad
spectrum
Anmerkungen:
- gabapentin, lamotrigene, toprimate, tigabine, levitarectam, zonisamide
- weened off seizure free 2-5yrs do
not stop abruptly , fall rsisk ,
monitor dizzyness/drowsiness
- common side effeect-
diplopia, drowsiness,
ataxia, mental slowing
- dose missed wait for next dose
- Toxicity- nystagmus, hand-
eye coordination, cognitive
functionaing and general
alertness
- Pregabalin
- Status
Epilepticus
- #1 lorezapam & diazempam
- follow by long acting
- intubated, EEG continuous
- children may need
general anasthesia
- OLDER age & drugs
- monitor Liver
function on
phyentoin
- Phenabarbitol,
carbmazepine,
primidone effects
cognitiion
- Safer for older
Anmerkungen:
- gabapentin, levatricetam, oxcarbmazepine, lamotrigene
- Nursing
management
- Surgery
Anmerkungen:
- (1) no satisfaction with drugs
(2) define electroclinical syndrome- need to which point (focal)
(3) confirmed epilepsy
- anterior
temporal lobe
resection
- Vagal
nerve
stimulation
Anmerkungen:
- not candidate for surgery alternative
- Teach pt. to avoid
MRIs, microwaves,
- adverse- cough,
hoarseness, dyspnea
& tingling at the neck
- Ketogenic
diet/biogenic
feedback
Anmerkungen:
- high fat, low carbohydrate
- if the pt. has
anticoagulant then
teach to watch for
bleeding
- Immediate
interventions
- Padded side rails (do not restrain)
- protect from injury
- Maintain patent airway/ensure ABC's
- Establish IV
- Loosen clothing
- Complications
- Status Epilepticus & Tonic-
clonic status elipeticus
(most dangerous)
Anmerkungen:
- Lorazempam &
Diazempam IV
bolus
- Subclinical Seizure
Anmerkungen:
- sedation (without external signs)
- SUDP
Anmerkungen:
- Sudden unexplainable death of epilepsy
- Psychologic - driving
sanctions, eployment
limitations, & social
stigma
- Severe injury/Death
- Chapter 59 Chronic Neurologic
Problem p. 1419
- Epilepsy- reoccuring
seizures (2 or more)
- Causes
- Metabolic
distrubances
Anmerkungen:
- acidosis, electrolyte imbalance, hypoglycemia, hypoxia, dehydration/water intoxication, alcohol & barbituate withdrawal
- Extracranial
seizures
outside the
brain
Anmerkungen:
- hypertension, SLE, DM, septecemia
- Generalized,
focal, febrile
- Age- determines most
common causes
Anmerkungen:
- Age after 50 - tumor/stroke
20-30- structural lesion, vascular disease, brain tumor
2-20 birth injury, infection, trauma, genetic factors
6months or younger - birth injury, severe cognential birth defect involving the CNS, infection, inborn errors of metabolism
- many are
idiopathic cause
unknown
- Gliolsis & change
in function of
astrocytes
- Genetic may
be a factor