Zusammenfassung der Ressource
Acute kidney injury
- Autoregulation of the kidney
- High blood pressure
- High renal flow (high
renal artery pressure)
- High GFR
- High tubular flow (No
reabsorption of Na)
- High NaCl (High
solute load)
- Macula densa (Very
sensitiive to Na in DCT)
- Secretes PRODUCTS
- Afferent arteriole
constriction
- Efferent arteriole dilation
- Myogenic hypothesis
- Stretching of vessels due to increased
pressure cause vasoconstriction which
keeps the RBF constant.
- Presentation
- Insomnia
- Oliguria
- Nausea and vomiting
- Hyperventilation
- Shock
- Causes
- Burns
- Infections
- Vomiting
- Spinal injury
- Hemorrhage
- Types
- Septic
- Anaphylactic
- Cardiogenic
- Hypovolemic
- Splenic injury
- Causes
- Penetrating
trauma
- Indirect trauma
- Blunt trauma
- Infections
- Management
- Operation
- Fluids
- Blood
transfusion
- Heart
transplant
- Catheter
- H2 blockers
- Steroids
- Antibiotics
- Causes in
the picture
- Complications
- Fluid buildup
- Kidney damage
- Chest pain
- Muscle pain
- Death
- Manage,ment
- Dialysis
- Diuretics
- Life style changes
- Statins
- ACE inhibitors
- Restore Ca and K levels
- Fluid resustication
- Healthy diet
- Exersice
- Cause
- Acute tubular necrosis
- Signs and symptoms
- High BUN
- Brown granular casts
- High urine osmolarity
- Nephrotoxic
- May be toxin
mediated
- Extensive
continous necrosis
- Intact basement
membrane
- Ischemic
- Patchy tubular
epithelialnecrosis
- Rupture of the
basement
membrane
- Injury and necrosis of
tubular epithelial cells
- Can lead to:
- Acid-base
disturbance
- Important Questions to ask!
- What is the osis?
(Alkalosis or Acidosis)
- What is the
cause of the osis?
- Was there
compensation?
- What are the functions that
can be impaired? (Picture)