Refractory period and conduction speed

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A-Levels Biology 5 (Nerves and Muscles) Mindmap am Refractory period and conduction speed, erstellt von harry_bygraves am 13/06/2013.
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Refractory period and conduction speed
  1. Neurones can generate nerve impulses over a wide range of frequencies. The frequency is limited by the absolute refractory period, during which the neurone is completely inexcitable, and the relative refractory period, during which it is less excitable than normal
    1. During the absolute refractory period the sodium ion channels are open. During this period, which lasts about a millisecond or less, a second stilumuls will not trigger a second action potential no matter how strong the stimulus is.
      1. The relatve refractory period follows the absoulte refractory period. It corresponds to the time when the extra potassium channels open to repolarise the membrane and potassium ions flood out of the axoplasm causing the membrane to become briefly more negative than the normal resting potential. During this period which lasts several milliseconds, a greater than normal stimulus is needed to indicate an action potential. However, the membrane becomes progressively easier to stimulate as the relative refractory period proceeds
        1. By limiting the maximum frequency of nerve impulses, the refractory period enables the nervous system to distinguish seperate stimuli and make coordination possible. IT ensures each nerve impulse is sperated from the next, with no overlapping signals, an essential feature for a system conveying frequency code information
          1. Only vertebrates have a myelin sheath surrounding neurones. Saltatory conduction increase the speed of propagation dramatically. Unmyelinated neurones transmit impulses at a maximum speed of about 1ms, while myelinated neurones have speeds of up to 100ms.
            1. Nerve fibres vary in diameter from about 0.5 to 1000 micrometers. Unmyelinated axons with wide diameters can transmit nerve impulses faster that those with small diameters. The conduction speeds of myelinated fibres also increase with axon diameter, but the advantage of myelination means there is no need for giant axons. The greatest advantage of mylinated axons comes from their small size, which allows a highly complex nervous system with high conduction speeds that does not take up much space.
              1. The conduction speed of a nerve impulse is strongly affected by temperature. Within limits, the higher the temperature, the faster the speed. This is mainly because the propogation of an impulse involves diffusion of ions, and the rate of diffusion increases with temperature as a result of the increased kinectic activity of the ions. Temperature also affects the integrity of membrances and the actions of enzymes involved in the active transport required to maintain the resting potential. At very high temperatures, membrances may be damaged and enzymes denatured, resulting in disruption of the nerve conduction.
                1. An important consequence of the relationship between temperature and conduction speed is that homoiotherms generally have fast responses irrespective of the enviromental temperature, while poikilotherms such as snakes can only respond quickly when their bodies have been warmed by, for example, the sun.
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