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15478876
Slippery Path (Abused drugs)
Beschreibung
Mindmap am Slippery Path (Abused drugs), erstellt von Abdelrahman Nouh am 08/10/2018.
Mindmap von
Abdelrahman Nouh
, aktualisiert more than 1 year ago
Mehr
Weniger
Erstellt von
Abdelrahman Nouh
vor mehr als 6 Jahre
21
0
0
Zusammenfassung der Ressource
Slippery Path (Abused drugs)
classified into
legal
alcohol
cigarettes
caffeine
inhalants
over the counter
codeine
vitamins
illegal
prohibited by UAE rules & laws
in 1995
death penalty for drug abusers
in 2016
rehabilitation rather than penalties
in centers
Ownak social
Erada
NRC
sections
psychiatric
medical
social work
psychology
provide services
treatment
education
examples
magic mushroom
heroin
cocaine and crack
marijuana
prescribed
barbiturates
stimulants
pain killers
anabolic steroids
mechanism of action
binding of the drug to the receptor
forming DR complex
produces effect
receptors can respond to
agonists
give the same effect of the natural drug
types
partial
inverse
antagonists
inhibits the binding of
demography
name: Ali
age: 26
reason of death
drug overdose
accidentally
intentionally
intolerable dose of
addiction type
poly-drug use
2 or more drugs used at the same time or over a short period of time
effects
depend on
types of drugs combined
more dangerous if 2 or more drugs with the same physical effects are taken together
ex: 2 stimulants: cocaine & ecstasy
toxicity
setting
time
place
person
ex: mood
leads to
addiction
dependency
risk factors
addicted parents
peer pressure
easy access to drugs in the community
involving at young age
puberty
activation of hypothalamo-pituitary gonadal axis
pulsatile GnRh
age
boys: 9-18
secondary characteristics
facial hair
loud, deep voice
developed muscles
broad shoulders
girls: 8-16
secondary characteristics
high pitched voice
development of breasts
broad pelvis & narrow shoulders
pubic & axillary hair
psychological issues
males
more aggressive
more production
females
more emotional
abnormalities
delay
boys: after 20
girls: after 17
precocious
below the age of 8
pseudo
only secondary characteristics
true
secondary characteristics & gametogenesis
preventive factors
employment
good income
parental education
if drug use stopped abruptly
withdrawal symptoms
sweating
depression
decreased dopamine
due to
tremors
nausea
insomnia
examination & investigation
abdomen
hepatomegaly
overwhelmed from
detoxification
phase 1
Functionalization/Biotransformation
reduction
hydrolysis
oxidation/hydroxylation
adding OH
by
phase 2
conjugation
adding conjugates to make the substance more polar and easily excreted
4G
glaucouronic acid
glycine
glutamine
glutathoion
M
methyl
S
sulfate
A
acetate
T
thiosulfate
cardiovascular
tachycardia
murmurs
neurological
cognitive impairment
tremor
blood test
liver enzymes
cytochrome P450
CBC
urine & serum toxicology
HIV
amylase & lipase
blood alcohol
appearance
nasal irritation
skin
needle marks
conjuctival irritation
Zusammenfassung anzeigen
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