Zusammenfassung der Ressource
Dysbiosis
- Dysbiosis is the shift in balance of normal microflora (type and quantity, metabolic activity and distribution) in the large intestine, resulting in a microbata which produces harmful effects
- Small intestine bacterial
overgrowth (SIBO)
- Causes
- Stress
- Poor diet
- Decreased digestive secretions
- Antibiotics
- Excessive alcohol
- Altered bowel motility
- Immune suppression
- Symptoms
- Local symptoms
- Indigestion
- bloating
- nausea
- diarrhea/constipation
- Associated with diseases
- Immune disregulation
- inflammation
- metabolic disturbances
- Systemic
- Autoimmune
- Rheumatoid arthritis
- Ankalising spondilitis
- Allergies
- UTI's
- Thrush
- GIT
- Irritable bowel syndrome
- inflammatory bowel disease
- enteric infections
- Leads to:
- Increased intestinal permeability, pathogens adhere to epithelial lining and damage tight junctions
- Inflammation: pathogens induce epithelial cells to secrete inflammatory cytokines,
adhesion molecules, and major hitocompatibility complex class II molecules, stimulates
immune cells eg neutrophils, monocytes, lymphocytes and eosinophils