Zusammenfassung der Ressource
Breast Lump
- Anatomy of the breast
- functional unit
- duct-lobular unit
- lies on
- serratis anterior
- pectoralis major
- external oblique
- Development of the breast
- prenatal
- starts at day 35 gestation
- formation of mammary line
- 6 months
- breast framework
- infant
- areola pigmented
- nipple projects
from growth of
underlying
mesoderm
- puberty till adulthood
- TANNER STAGES
- Breast Cancer
- Genetics
- Subtypes
- Luminal A
- ER+
- SERMs
- Luminal B
- ER+ Her2+
- Her 2+
- ER -ve, Her 2+
- trastuzumab
- Basal like
- ER-, HER2-
- chemotherapy
- Risk factors
- BRCA-1 and BRCA-2
- increased oestrogen exposure
- age at first birth
- early menarche, late menopause
- obesity
- non-invasive
- ductal carcinoma in situ
- malignant proliferation of ductal cells
- doesn't cross BM
- comedocarcinoma
- central necrosis and calcification
- paget disease
- intraepithelial adenocarcinoma
- eczematous lesion on nipple
- invasive
- ductal carcinoma
- DCIS crosses BM
- nipple retraction
- skin dimpling
- lobular carcinoma
- single sheet of cells
- decreased E-cadherin expression
- medullary carcinoma
- fleshy, cellular,lymphocytic infiltrate
- inflammatory
- lymphatic invasion and blockage
- p'eau d'orange
- screening
- mammogram