Zusammenfassung der Ressource
FMS 1 Cell Structure & Function (Week
1)
- CELL
- = the vehicle for transmission of genetic info in all organism
- Theory by MJ Schleiden & T Schwann 1839
- composed of 1/> cells
- Exist before
- Vital function
- contain Hereditary info
- Characteristic
- Self-contained & Self-maintening
- Need nutrient
- nutrient --> energy
- Specialized function
- Reproduce
- Stores its own activity instruction
- Use protein as catalyst
- Amino acids bind and act as enzyme
- Enclosed in plasma membrane across which
nutrient & waste materials must pass
- DNA
- Components
- 4 nucleotides : A,C,T,G
- A <-> T, C <-> G
- Deoxyribose
- Phosphat compound
- Structure
- Double helix
- Herited
- RNA translation
- PROCES ???
- Prokaryotes
- Cell Structure
- Flagella
- = long, slender projection composed of
microtubule, serve to propel the cell
- Types
- Monotrichous
- Peritrichous
- Amphitrichous
- Lophotrichous
- Cell Wall
- = a fairly rigid layer surrounding the cell
provide structural support, protection, filtering
- CLASSES
- Gram-negative
- inner membralikan -> periplasmic space ->
peptidoglycan -> outer membrane -> porin protein -> LPS
- Gram-positive
- inner membrane -> peptidoglycan -> teichoic acid
- Cell capsule
- = layer outside cell wall composed of polysaccharides
serve to protect bacteria from phagoctosis
- PLasma membrane
- = composed of protein & phospholipid, serve as permeability
barrier, enzyme, transport solutes, energy generation
(combined mitochondria), DNA anchoring, chromatid separation
- Pili
- = composed of
protein, for DNA
transfer during
conjugation
- Ribosomes
- For protein synthesis
- Chromosomes
- Genetic material
- Plasmid
- Extrachromosomal genetic material
- Multidrug resistance
- Why ?
- Enzymatic deactivation of antibiotic
- Decreased cell wall permeability to antibiotic
- Altered target sites of antibiotic
- Efflux mechanism to remove antibiotic
- increased mutation
- Solution
- Only use antibiotic for bacterial infection
- Use specific antibiotic for specific bacteria
- Don't stop antibiotics ASAP symptoms improve
- Prokaryotes VS Eukaryotes