Zusammenfassung der Ressource
Management of Anticoagulation
- Heparin
- MOA: Indirect Thrombin Inhibitor - -
Enhances the effects of
Antithrombin III
- Indications: VTE, DVT prophylaxis,
ACS, line patency
- Dose: Patient specific based
on indication and aPTT
- VTE: DVT or PE (& AFIB)
- IV (USED ALL THE TIME)
- BOLUS: 80 UNITS/KG (MAX 10,000 UNITS) THEN
--> CONTINUOUS INFUSION: 18 UNITS/KG/HOUR
(MAX 2,000 UNITS PER HOUR)
- SQ: 333 UNITS/KG
FOLLOWED BY: 250
UNITS/KG Q12H
- ADRs: Bleeding, bruising,
decreased platelets
- Monitoring: aPTT
- Drug interactions: Some - - pt on
another antiplatelet/anticoagulant
- Food interactions: no
- Counseling / Diet: Typically an
inpatient medication
- Reversal? YES