Zusammenfassung der Ressource
Endocrine System Drugs
- Diabetes
- Type 1
- Caused by autoimmune
attack against the
pancreatic beta cells.
Prevalent in children. .
- Treatment:
Insulin
replacement
therapy
- Type 2
- Insensitivity of cells to insulin
signaling. Developes from long
term environmental factors
such as, a sedentary lifestyle,
and being overweight/obese.
- Treatment: Exercise and
dietary changes to promote
weight loss, medications,
and hormone therapy,
- Gestational
- Insensitivity of cells to insulin
signaling during pregnancy occurs
when the normal insulin resistance
that occurs in pregnancy becomes
excessive and leads to
hyperglycemia in the mother.
- Treatment: Blood glucose
monitoring, dietary changes,
exercise, weight gain limitations,
and cesarian delivery
- Types of Insulin: - Rapid acting - short
acting - intermediate acting - long
acting
- IV (only administered in
emergencies), intermittent
subcutaneous injection, or
by continuous infusion
pump
- Treatment for hypoglycemia: Consume 15-20
grams of glucose or simple carbohydrates.
Recheck your blood glucose after 15 minutes.
If hypoglycemia continues, repeat. Once
blood glucose returns to normal, eat a small
snack if your next planned meal or snack is
more than an hour or two away.
- Thyroid disorders
- Hyperthyroidism
- Radioactive iodine,
Anti-thyroid
medications, Beta
blockers, Surgery
(thyroidectomy).
- Hypothyroidism
- synthetic (man-made)
thyroid hormone T4.
- Oral hypoglycemic
(Type 2 diabetes)
- Insulin secratogogues, insulin
sensitizers, a-glucosidase inhibitors,
glucagon-like peptide agonists
- Adverse effects:
Hypoglycemia, wt gain
- Increases insulin cell
receptors, increases abil
of cell to bind insulin
- Adrenal disorders
- Addisons disease
- Hormone replacement. Prednisone
(replace cortisol), fludrocortisone
(replaces aldosterone)
- Cushings disease
- Remove causative
drug, surgery,
radiotherapy
- Conn's disease
- Removal of tumor, adrenalectomy
Meds: spironolactone (Aldactone)
eplerenone (Inspra) amiloride
(Midamor)