Zusammenfassung der Ressource
FAISAL WORKS IN HIS
GARDEN
- conduction system of
the heart
- AP in ventricular
myocyte
- phase 0: Na+ influx
- phase 1: Na+ close & K+ open
- phase 2: Ca2+ influx (L-type)
- phase 3: K+ efflux
- phase 4: K+
conductance
- AP in SA node
- phase 0: Ca2+ influx
- phase 4: Na+ influx by
HCN channels
- phase 3: K+ efflux
- Heart anatomy
- Grooves
- Atrioventricular
(coronary) groove
- Anterior
interventricular
groove
- Interatrial groove
- Posterior
interventricular groove
- Pericardium
- inner Serous
pericardium
- Parietal layer
- Visceral layer
- Outer fibrous
pericardium
- Located in the inferior
mediastinum
- External features
- 4 Surfaces
- Sternocostal
surface
- Atrial
portion
- Ventricular
portion
- Diaphragmatic
surface
- Left “pulmonary”
surface
- Right “pulmonary”
surface
- 4 borders
- Left border
- Right border
- Superior border
- Inferior border
- Base
- Directed backward, to
the right
- Formed by left atrium
/ part of right atrium.
- Apex
- Directed downwards,
forwards,to the left
- Lie in the 5th
IC
- Formed by left
ventricle
- Heart wall
- Epicardium
- Myocardium
- Endocardium
- Sick Sinus Syndrome
- Causes
- Neuromuscular diseases
- Inflammatory
diseases
- Age
- Obstructive sleep apnea
- Rare genetic
mutations
- Pathophysiology
- Mechanism of sinus
bradycardia
- lower MDP
- Higher threshold
- Reduced sodium
current flow
- Mechanism of tachycardia
- AV node ectopic focus
- Enhanced SA
automaticity
- manifestations
- Bradychardia-tachycardia
syndrome
- Sinus arrest
- SA block
- chronotropic
incompetence
- Management
- Non-Pharmacological
- Pacemaker
- Pharmacological
- Class I: Na+ Channel
Blockers
- Class Ia
- Class Ib
- Class Ic
- Class IV: Ca+2 -Channel
Blockers
- Class II: Beta-blocker
- Class III: K+-Channel Blockers
- Risk factors
- High blood
pressure
- High cholesterol
- Excess body weight
- Lack of exercise
- history of congenital
heart disease
- Unconsciousness &
Fainting
- Signs to check for:
- Pain responds
- unresponsiveness
- Verbal stimulus
- Awake
- arrhythmias
- Brady arrhythmias
- tachyarrhythmias