Zusammenfassung der Ressource
STEMI
- MONA
- Beta Blocker
- Primary PCI
- Abciximab ASAP before PCI
- Alternative GP IIb/IIIa inhibitor
- Thrombolytic
- Tissue Plasminogen Activators
- Non-selective (not used)
- Streptokinase
- Anistreplase
- Urokinase
- Selective
- Alteplase
- Reteplase
- Tenecteplase
- Anticoagulation with thrombolysis for >48 h
- d/c after PCI or CABG
- UFH 60 units/kg bolus then
12 units/kg/h
- Monitor aPTT and H/H
- IF <75 enoxaparin 30 mg IV bolus then 1 mg/kg SQ q12
- If >75 no bolus and 0.75
mg/kg SQ BID
- CrCl <30 ml/min use 1
mg/kg SQ q24h
- Contraindicated in dialysis pts.
- Fondaparinux 2.5 mg IV bolus
then 2.5 mg SQ q24h
- Monitor H/H and SCr
- Contraindicated in CrCl
<30 ml/min
- If stented, add clopidogrel
- 300 mg load if <75
- Withhold >5 days
pre-CABG
- Prasugrel
- NOT studied with medical
management (thrombolytic
monotherapy)
- Ticagrelor
- 180 mg load then 90 mg BID
- Aldosterone Antagonists
- Statin
- ACEi
- Start after SL
nitroglycerin, beta blocker
- Lifelong if LV dysfunction, HF, anterior MI
- Caution hypotenstion and
chronic renal failure
- Contraindicated in acute renal failure
- Oral only, no IV