Zusammenfassung der Ressource
Acetylcysteine
- Indications
- Paracetamol Poisoning antidote
- In IV
form
- Overdosage can
cause
ANAPHLACTOID
REACTION but
histamine release
is not bcoz of IgE,
so it can be started
once again at
lower infusion rate
after reaction
stopped(by
stopping infusion
and giving
antihistamine
and/or
bronchodilator)
- It replenish
glutathione
in body
- 21 hr infusion, check
dose
- Effective if given within 8 hrs of
a single overdose of
paracetamol
- prevent contrast nephropathy
- Mechanism not
really known, could be due to its antioxidant effect
- 600-1200 mg PO/12hrly for 2
days begining the day before
procedure
- mucolytic
- Reduce Viscosity of
respiratory secretion
- can cause bronchospasm, so give
SALBUTAMOL before starting
- it liquify mucus, it can aid in
sputum clearance as well
- 2.5-5 mL 10%
soln/6 hrly
- 20% available
dilute to 10%
- In
nebulized
form
- eye drops act as eye
lubricant
- along with
hypermellose
- llube brand
- Monitor INR (most
sensitive
marker),ALT,creatinine
concentration