Zusammenfassung der Ressource
Biological Oxidation and
Hydrogen Transfer Systems
- Oxidation: may or may not involve molecular oxygen.
- removal of an electron from a metal
- Fe2+ -> Fe3+ + e-
- removal of electrons plus protons from a
hydrogenated compound
- AH2 -> A + 2e- + 2H+
- electrons must be transferred
to an electron acceptor
- NAD+
- initial electron acceptor
- full name: nicotinamide
adenine dinucleotide
- bases are adenine and nicotinamide
- oxidation and reduction is
undertaken by nicotinamide
- base-sugar-phosphate-phosphate-sugar-base
- can accept two electrons plus a protein as a hydride ion
- co-enzyme for a number of dehydrogenases
- FAD and FMN
- also electrons carriers
- FAD = flavin adenine dinucleotide
- FAD is permanently attached to its
proenzyme - it is a prosthetic group.
- Main phases of glucose oxidation
- oxidation of glucose = delta G of 2820 kJ mol
- oxidation results in 30 ATP being produced
- fiirst phase = glycolysis where two
C3 fragments are produced.
- second phase = C3 fragments are
oxidised to carbon dioxide and water
- third phase = energy from re-oxidation of
reduced carries is used to generate ATP