lymphoma

Beschreibung

Mindmap am lymphoma, erstellt von maitha alyahyaee am 02/09/2021.
maitha alyahyaee
Mindmap von maitha alyahyaee, aktualisiert vor 8 Monate
maitha alyahyaee
Erstellt von maitha alyahyaee vor etwa 3 Jahre
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Zusammenfassung der Ressource

lymphoma
  1. DD of lymphadenopathy
    1. general/local?
      1. site?
        1. infection? autoimmune? malignancy?
        2. Anatomy of lymph nodes
          1. Scattered ,Covered by a capsule of dense connective tissue, Trabeculae divide the node into ( Cortex / Medulla )
            1. cortex
              1. Follicles of B cells, Germinal centers
                1. Rich in T cells, Dendritic cells
              2. medulla
                1. Medullary cord, Medullary sinus
            2. treatment
              1. Low-grade NHL (initial stages): radiotherapy Low-grade NHL (advanced stages): palliative chemo High-grade NHL: chemotherapy
                1. R-CHOP Therapy
                  1. ABVD
                    1. BEACOPP
                    2. classification
                      1. hodgkin lymphoma HL
                        1. Nodular sclerosis, Mixed cellularity, Lymphocyte-rich, Lymphocyte-depleted
                          1. reedsternberg cells
                            1. sequence/order fashion
                              1. B symptoms
                                1. high inflammation (cytokines)
                          2. NHL
                            1. b cells
                              1. follicular, diffuse
                              2. t cells
                                1. poor prognosis
                                  1. random
                              3. risk factors
                                1. genetic mutations (myc,bcl2)
                                  1. viral infection (EBV, HTLV1)
                                    1. pathogenesis
                                      1. Age, male, AID
                                        1. environmental factors
                                        2. complications
                                          1. weakened immunity
                                            1. pressing nearby structures
                                              1. spread
                                                1. nausea, fatigue, infertility (treatment related)
                                                  1. psychological
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