Zusammenfassung der Ressource
leishmaniasis
- signs and symptoms
- Cutaneous leishmaniasis.
- sores on skin that can change in
appearance and size over time.
- Mucocutaneous leishmaniasis.
- Stuffy nose
- Mouth or nose sores
- Frequent nose bleeds
- Visceral leishmaniasis.
- Weight loss
- fever
- Swelling of the liver and spleen
- Abnormal blood tests
- risk factors
- traveling to endemic regions
- alterations in temperature
- poor socio-economic status
- Immunosuppression
- complications
- Septicemia
- Splenic rupture
- Secondary bacterial infection,
including pneumonia and tuberculosis
- Edema
- hyperpigmentation
- epidemiology
- About 95% of CL cases occur in the Americas, the Mediterranean basin,
the Middle East and Central Asia
- cutaneous leishmaniasis, estimates of the number of new cases per
year have ranged from approximately 700,000 to 1.2 million or more.
- investigation
- Blood Smear : Giemsa stain microscopy for amastigote
- Skin Biopsy: by scraping one of the ulcers
- Serological test -ELISA
- bone marrow biopsy
- management
- Sodium stibogluconate
Meglumine antimoniate
- first-line agents for cutaneous and visceral
leishmaniasis.
- inhibition of glycolysis in the parasite at
the phosphofructokinase reaction.
- Adverse effects:
- Pancreatitis
- elevated liver enzyme
- arthralgias
- myalgia
- Miltefosine
- interfere with phospholipids in parasitic
cell membrane to induce apoptosis.
- which organ it affects
- skin
- histology
- functions
- protection
- heat regulation
- excretion
- sensation
- absorption
- causes of skin itchiness
- skin conditions
- eczema
- psoriasis
- dry skin
- internal diseases
- kidney disease
- liver disease
- blood disease
- allergic reaction
- food
- medicine
- pollen
- bug bite
- skin cancer
- stages of wound healing
- Hemostasis
- inflammation
- proliferation
- remodeling
- types of skin lesions
- patch
- nodule
- macule
- plaque
- papule
- bullae
- vesicle
- neoplasms
- Keratoacanthoma
- actinic keratosis
- bowen's disease
- squamous cell carcinoma
- basal cell carcinoma
- causes
- Leishmaniasis is caused by infection with Leishmania
parasites, which are spread by the bite of phlebotomine
sand flies.
- prevention
- Wear clothing that covers as much skin as possible
- Spray indoor sleeping areas with insecticide.
- Use insect repellent on any exposed skin and on the
ends of your pants and sleeves.