Zusammenfassung der Ressource
Mutations
- various sorces
- lead to changes in the amino acid sequence
- can change cell function
- not all mutations cause problems
- if hydrophobic amino acid changes to hydrophobic, no drastic change
- nonsense
- early stop codon
- shinks protein
- silent
- changes nucleotide that doesn't change amino acid specified codon
- changes genotype not phenotype
- missense
- changes nucleotide that does
change amino acid specified
codon
- change in primary structure of protein
- frameshift
- addition/deletion of a nucleotide
- reading frame is shifted massive missense