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Diuretics

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Medicine Pharmacology Mindmap am Diuretics, erstellt von Shaima Amanda am 10/01/2014.
Shaima Amanda
Mindmap von Shaima Amanda, aktualisiert more than 1 year ago
Shaima Amanda
Erstellt von Shaima Amanda vor fast 11 Jahre
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Zusammenfassung der Ressource

Diuretics
  1. Extra-renal
    1. Renal
      1. Natriuretics/ Saluretics
        1. Loop diuretics
          1. act on thick ascending
            1. Sulfonamides
              1. Frusemide
                1. Torsemide, Bumetanide
                2. Non-sulfonamides
                  1. Ethacrynic acid
                3. Moderate efficacy diuretics
                  1. Thiazide
                    1. Acts on DCT
                      1. Inhibits NaCl reabsorption
                        1. Increase sodium and water excretion
                          1. hypovolemia, hypercalcemia, hypokalemia, alkalosis, hypocholeremia, hypomagnesemia, hyperuricemia
                        2. Antagonist-> probenecid
                          1. Contraindicated during renal insufficiency
                            1. Has diuretic effect, antidiuretic effect, antihypertensive effect, hyperlipidemia, hyperglycemia, hyperuricemia
                            2. Act on diluting segment
                            3. Low efficacy diuretics
                              1. CAI
                                1. ACI-tazolamide
                                2. K retaining
                                  1. AldoSterONE Antagonist
                                    1. SpironolactONE
                                    2. Non-aldosterone antagonist
                                      1. Amiloride
                                        1. Triamterene
                                  2. Osmotic diuretics
                                    1. Mannitol
                                    2. Acidifying diuretics
                                      1. NH4Cl
                                    3. Reduce hypertension
                                      1. Reduce Renal blood flow and GFR
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