478259
Beschreibung
Mindmap von v.djabatey, aktualisiert more than 1 year ago
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Erstellt von v.djabatey
vor fast 11 Jahre
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The inflammatory myopathies
- benign acute myositis
- assumed post-viral phenomenon
- often follows an upper resp tract infection
- runs a self-limiting course
- runs a self-limiting course
- often follows an upper resp tract infection
- pain &
weakness in
the affected
mm
- CPK usually raised
- assumed post-viral phenomenon
- dermatomyositis
- systemic illness
- probably due to an angiopathy
- probably due to an angiopathy
- onset 5-10 years old
- acute
- typically insidious
- fever
- misery
- eventually
symmetrical mm
weakness
- mainly proximal
- mainly proximal
- pharyngeal mm
involvement
- swallowing
affected
- swallowing
affected
- heliotrope (violaceous) rash
- characteristic
- eyelids
- extensor
surfaces of
e.g.
- elbow
- elbow
- characteristic
- periorbital
oedema
- subcutaneous
calcification
- fever
- acute
- Ix
- raised ESR, CRP possibly
- muscle biopsy
- inflammatory
cell infiltrate
& atrophy
- inflammatory
cell infiltrate
& atrophy
- raised ESR, CRP possibly
- Mx
- physiotherapy
- prevent
contractures
- prevent
contractures
- corticosteroids
- mainstay of Rx
- continue @
tailored dose for
2 years
- mainstay of Rx
- immunosuppressants
- methotrexate
- ciclosporin
- methotrexate
- physiotherapy
- mortality= 5-10%
- systemic illness
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