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Key Microbiological Milestones
- First Microscope
- Created by Anthony van Leeuwenhoek in 1676
- Was Monocular, could magnify specimens up to 50 times
- Created by Anthony van Leeuwenhoek in 1676
- Spontaneous Generation
- The belief that living organisms could
develop from non-living matter
- Challenged by Redi
- Placed meat into 3 different jars
- Completely Covered
- Nothing Formed
- Nothing Formed
- Left Open
- Flies flew in and laied eggs
on the meat
- Flies flew in and laied eggs
on the meat
- Covered with a gauze
- Maggots came to the gauze
- Was concluded that air is
critical, it had a 'life force'
- Was concluded that air is
critical, it had a 'life force'
- Maggots came to the gauze
- Completely Covered
- Furthered by Louis Pasteur
- Used a series of handmade flasks
- Positive Control
- Left Open
- Contamination occured
- Contamination occured
- Left Open
- Negative Control
- Sealed completey
- No contamination
- No contamination
- Sealed completey
- Test Flask
- Was left open BUT was Swan-necked
- Stayed fresh as microbes got trapped in the swan-neck
- Stayed fresh as microbes got trapped in the swan-neck
- Was left open BUT was Swan-necked
- Positive Control
- Used a series of handmade flasks
- Placed meat into 3 different jars
- The belief that living organisms could
develop from non-living matter
- Pioneers
- Edward Jenner
- Smallpox
- Cowpox had similar anti-bodies so being
exposed to Cowpox made you become
immune
- Cowpox had similar anti-bodies so being
exposed to Cowpox made you become
immune
- Smallpox
- Joseph Lister
- Introduced
anaesthesia and
asepsis
- Asepsis is working without infection
- Asepsis is working without infection
- Antiseptic Surgery
- Created the Carbolic Acid Spray
- By product of the coal industry, was very irritating and corrosive
- By product of the coal industry, was very irritating and corrosive
- Created the Carbolic Acid Spray
- Introduced
anaesthesia and
asepsis
- Robert Koch
- Identified Anthrax disease cycle
- Used in biowarfare
- Used in biowarfare
- Identified organisms that cause tuberculosis
- Formulated the "Koch's Postulates"
- Describes a set of basic procedures used
to show that a specific micro-organism
causes a particular disease
- Links the cause and effect of a
disease and emphasises the
importance of the lab cultures
- Links the cause and effect of a
disease and emphasises the
importance of the lab cultures
- Describes a set of basic procedures used
to show that a specific micro-organism
causes a particular disease
- Identified Anthrax disease cycle
- Alexander Fleming
- Penicillin
- Penicillin
- Jonas Salk
- Polio Vaccine
- Polio Vaccine
- Watson and Crick
- Structure of DNA
- Structure of DNA
- Edward Jenner
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