Roles of Dopamine in the Brain by Tosin

Beschreibung

Roles of Dopamine in the Body
Tosin O
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Tosin O
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Zusammenfassung der Ressource

Roles of Dopamine in the Brain by Tosin
  1. Neuroendocrine
    1. Controlling Prolactin Secretion
      1. See Tuberoinfundibular Pathway in Dopamine Pathway Mind Map
    2. Schizophrenia
      1. Dopamine Hypothesis of Schizophrenia
        1. Hyperactivity of Dopamine = Positive and Negative Symptoms as well as Cognitive Deficits

          Anmerkungen:

          • Cognitive Deficits = Mesocortical  Include =  working memory, visual/verbal learning
          • Others included cont. = speed of processing information, attention and Reasoning plus problem solving
      2. Basal Ganglia (BG)
        1. Overactivity = BG disturbances = unpurposeful movement (tremor) - Hyperkinetic

          Anmerkungen:

          • Tardive Dyskinesia = cause
          1. Underactivity = Movement disorder - hypokinetic
          2. Vomiting
            1. Area Postrema (Emesis Centre in Medulla Oblongata)
              1. Chemoreceptor trigger zone = senses blood toxicity

                Anmerkungen:

                • Drugs altering Dopamine levels = Area Postrema = highly sensitive
                1. High density of Dopamine Receptors
                  1. High Dopamine = Vomit but Dopamine Block = Anti-emesis
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