4972438
Beschreibung
Mindmap von Bee Brittain, aktualisiert more than 1 year ago
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Erstellt von Bee Brittain
vor mehr als 8 Jahre
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1.9 Enzyme Inhibition
- Competitive Inhibition
- Bind to active site of enzyme - COMPETE against substrate
- Inhibitors will have a similar shape to substrate
- Block substrate from getting to active site by binding to enzymes active
site
- NO ENZYME-SUBSTRATE COMPLEXES formed
- decreased rate of reaction
- decreased rate of reaction
- NO ENZYME-SUBSTRATE COMPLEXES formed
- How much of enzyme inhibited depends on relative concentrations of inhibitor and substrate
- Higher conc. of inhibitor = occupy most active sites
- Higher conc. of substrate = chances of ENZYME-SUBSTRATE COMPLEXES increase
- So increasing the conc. of substrate will increase rate of reaction (up to a point)
- So increasing the conc. of substrate will increase rate of reaction (up to a point)
- Higher conc. of inhibitor = occupy most active sites
- Bind to active site of enzyme - COMPETE against substrate
- Non-Competitive Inhibition
- Bind to Allosteric site - NOT COMPETING against substrate
- Inhibitors can be completely different shape to substrate
- Binding to the allosteric site causes the active site to change
shape = substrate no longer fits so can't bind
- NO ENZYME-SUBSTRATE
COMPLEXES
- NO ENZYME-SUBSTRATE
COMPLEXES
- Increasing substrate concentration has no effect on reaction
rate
- Bind to Allosteric site - NOT COMPETING against substrate
Medienanhänge
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