Zusammenfassung der Ressource
Immunology
- Immunology is the study of immune system that includes various
cells, tissues and organs, working collectively and defend against
harmful pathogens, cells and substances.
- Lines of Defences:
Anmerkungen:
- 1. First line
- External physical barriers
e.g skin2. Second line Internal physiological barrierse.g inflammation3. Third line- Adaptive immune response
- Components of Immune System
- Cardiovascular system
Anmerkungen:
- Mononuclear Phagocyte System
Anmerkungen:
- - Network of reticular fibre
- Phagocytes (macrophages)
- Lymphatic System
- Primary lymphoid organ
Anmerkungen:
- Secondary Lymphoid organs
Anmerkungen:
- 1. Adenoid
2. Tonsils
3. Lymph nodes
4. Spleen
5. Mucosa-Associated Lymphoid Tissue (MALT)
- Lymph circulatory system
Anmerkungen:
- Cells of Immune system
- Leukocytes
Anmerkungen:
- - Have nuclei
- Involved in phagocytosis, inflammation, adaptive immune response
- Platelets
Anmerkungen:
- - Do not have nuclei
- Involved in inflammation and blood clotting
- Basophil
Anmerkungen:
- Neutophil
Anmerkungen:
- Killing the invading microbes
- Eosinophil
Anmerkungen:
- Defense against parasitic infection.
- Involve phagocytosis
- Monocytes
Anmerkungen:
- Lymphocyte
Anmerkungen:
- Response to foreign invaders in the body
- Mast cell
Anmerkungen:
- Involve in wound healing and defense against pathogen
- Natural killer cells (NK cells)
Anmerkungen:
- Host rejection of both tumors and virally infected cells
- Lines of Defense
- Innate immune response
Anmerkungen:
- - Non specific
- IMMUNE RESPONSE PREFORMED
- Response magnitude is similar during the first and subsequent encounters
- No memory stored
- First line
- Saliva
- Mucus
- Tears
- Stomach acid
- Skin
- Second line
Anmerkungen:
- Fever
Anmerkungen:
- Initiated by pyrogens;
Change the hypothalamus
- Inflammation
Anmerkungen:
- 1. Redness
2. Heat
3. Pain
4. Oedema
- Stages:
1. Tissue injury
2. Dilation and increased leakiness of local blood vessels
3. Phagocytes- phagocytosis
- Phagocytosis
Anmerkungen:
- 1. Attachment
2. Ingestion
3. Killing
4. Degradation
- Antimicrobial proteins
Anmerkungen:
- 1. Interferons
Iron-binding proteins
3. Antimicrobial peptides
- Adaptive immune response
- Third line