Zusammenfassung der Ressource
Biological approach to
explaining OCD (NEURAL)
- Abnormal levels of
neurotransmitters
- Dopamine is abnormally high in
those with OCD
- Animal studies
- High doses of drugs enhancing
levels of dopamine, induce
stereotyped behaviour of OCD
- Lower levels of serotonin are
associated with OCD
- Antidepressants increasing the
serotonin levels have proved effective in
treating OCD
- Abnormal brain circuits
- Several areas in the frontal
love have been thought to
be abnormal in those with
OCD.
- Caudate nucleus normally supresses
signals from the orbitofrontal
cortex.
- The OFC sends signals to the
thalamus about worrying
things, i.e. germs.
- When the caudate nucleus
is damaged, it fails to
supress minor worry signal
and the thalamus is
alerted, sending signals
back to OFC and acting as a
worry circuit.
- Supported by PET scans taken while
symptoms are active, i.e. holding a
dirty cloth, showing the OFC to be
active
- Serotonin and dopamine are linked to
those areas of the frontal lobes and
serotonin is thought to play a key role
in the operations of the OFC.
- Abnormal serotonin levels may
also cause areas to
malfunction.
- Dopamine is linked too as it is
the main NT of the basal
ganglia and high levels of it
lead to over activity in this
region