Fundamental of Cell Biology

Common biological & characteristics of cell
1. Properties of cells that define cells
  1. Growth
  2. Reproduction
  3. Response to stimuli
  4. Information processing
  5. Metabolic activity
2. Membrane bound
  1. Complex internal architecture (membrane and protein structures)
    1. Aqueous internal space (cytosol)
      1. Either free or attached other cells
Stem cells and asymetric cell division
1. mitosis
2. differentiation
3. apoptosis
4. symmetric & asymmetric division lead to vary cell phenotypes
  1. asymmetric determined by environment
5. stem cells and cellular differentiation
  1. totipotent (zygote)
    1. pluripotent (embryonic stem cells)
      1. multipotent/unipotent (adult stem cells)
  2. can divide into
    1. other stem cells
    2. specialised cells
Nobel Prize winners
1. discovery of mature cells can reprogrammed to become pluripotent
  1. Sir John B. Gurdon & Shinya Yamanaka (2012)
2. discovery and development of the green fluorescent protein GFP
  1. Martin, Osamu & Roger Y Tsien
Experimental organisms
1. Model organisms (including humans)
  1. Yeast
  2. Roundworm
  3. Fruitfly
  4. Zebrafish
  5. Mice
2. Lab cell culture
  1. HeLa cell culture
  2. Propagate virus using mammalian cell culture
Biomedical applications of cell biology

Zusammenfassung der Ressource

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