Zusammenfassung der Ressource
Parkinson's Disease
- Physical Effects
- The lack of dopamine
impairs movement by
decreasing a person's
control over their body.
These symptoms are
known as Parkinsonian
Motor Symptoms.
- Parkinsonian
Motor Symptoms
- Muscular Rigidity
- The inability for the
muscles to relax normally,
causing pain
- Postural and gait impairment
- Causes unsteady
movements and a stooped
posture
- Bradykinesia
- Is the slowness of initiation of voluntary
movement with progressive reduction in
speed and amplitude of repetitive actions
- Rest Tremor
- Is most common in the hands
and forearms. It appears when
the limbs are relaxed and it
disappears with active
movements
- Pathophysiological Cause
- Causative factors of Parkinson's remain unknown.
But Parkinson's is a neurodegenerative condition
due to a deficiency of not only dopaminergic cells,
but also cholinergic, noradrenergic, serotonergic,
histaminergic and glutaminergic cells, accounting
for the wide clinical spectrum motor and
non-motor functions that are affected
- Non-motor features including
cognitive impairment, depression,
hallucinations, autonomic
features and sleep problems are
also affected by Parkinson's
Disease
- A decrease in dopamine
production leads to the
impairment of motor function
- Cholinergic cells are responsible for
the activation during both
wakefulness and rapid eye
movement sleep
- Spiritual Effects
- Social Effects
- Cognitive Effects
- Sleep Deprivation due to lack
of cholinergic cells in the
body as well as the
uncomfortable and
uncontrollable effects of rest
tremors and the pain caused
by muscular rigidity
- A sleepy fatigued person is
accident prone, has poor
memory, is judgement
impaired and more likely to
make mistakes, bad decisions
and have a loss of motivation
- Holistic Effects