Zusammenfassung der Ressource
Vaccination - History
- Louis Pasteur
- 1857 - Employed to find the explanation
for the souring of sugar beet used in alcohol
industry.
- He blamed germs.
- He proved they were in the air by
sterilising some water and keeping it
in two flasks. One was closed and
stayed sterile. The other bred
micro-organisms.
- Chicken Cholera Vaccine
- He heard about
Koch's good work
and came out of
retirement in 1877.
- This caused many other
scientists to join the new
field of bacteriology.
- Both he and Koch worked with large
teams in the France/Germany
competition for national prestige.
- Charles Chamberland was in Pasteur's team.
- He was told to inject chickens with chicken cholera but he forgot as he went on holiday.
- He left the cholera culter on his desk and injected it into the chickens when he returned.
- They survived and they tried again and they survived again.
- They realised that it was because it was
weakened by being left and it made the
chicken's immune like Jenner's cowpox had.
- Rabies
- Rabbit spines dried and tested on a dying boy. He lived.
- Found cure for anthrax in sheep.
- 1881 - Demonstrated in public.
- Science
- 18th Century - Micro-organisms had been seen through microscopes
- Scientists thought they were caused by disease.
- Spontaneous Generation
- They thought that it was a random thing or
that it came from gases in the air called
miasmas
- Robert Koch
- Linked diseases to the microbe that caused them.
- He developed a solid
medium to frow cultures
and practise dye techniques
in to colour microbes.
- He experimented on
his daughter's mice.
- 1875 - Identified anthrax
spores and the bacteria that
causes septicaemia,
tuberculosis - 1882 and
cholera - 1883.
- Edwin Kleb
- Diphtheria Germs
- Others proved an antitoxin could cancel out
toxinx produced by germs.
- Reduce effects.