Zusammenfassung der Ressource
arthroma
- Damage to lining of artery caused by carbon monoxide, hypertension or high levels of LDLS
- Blood LDLs pass into the tunica intima and accumulate-stimulate immune responce
- Macrophages engulf the LDL in the tunica intima, die and turn into foam cells
- Over time a fatty streak forms made of LDL molecules and foam molecules and foam cells (first visible sign of atherosclerosis)
- Smooth muscle cells grow around the fatty streak. Smooth muscle cells cause the proteins collagen and elastin to be laid down forming a fibrous cap
- LDL's continue to build up behind the fibrous cap eventually forming an arthroma or plaque
- The arthroma may burst causing blood clots to form and further increasing the thickness of the fibrous cap
- Eventually the lumen becomes narrower and restricts the flow of blood