774486
Laboratory tests
- Diagnostic
Testing
- add information to
pt database
- Screening
- identify risk
factors
- asymptomatic patients
- identify risk
factors
- Diagnosis
- Est. of exclude
press. of disease
- symptomatic patients
- Est. of exclude
press. of disease
- Patient Management
- evaluate
severity of
disease
- estimate prognosis
- monitor course
of disease
- progression
- stability
- resolution
- progression
- Detect disease
recurrence
- Select Meds and
adjust therapy
- evaluate
severity of
disease
- Performance of Diagnostic Tests
- Preparation
- Test
- specimen
- most crucial element for
properly conducted test
- most crucial element for
properly conducted test
- specimen
- Patient
- Fasting
- glucose
- triglyceride
- glucose
- posture
- renin
- renin
- Na intake
- aldosterone
- aldosterone
- Strenuous Exercise
- creatine kinase
level may be
abnormal
- creatine kinase
level may be
abnormal
- Fasting
- Test
- Specimen Collection
- patient ID
- 2 identifiers
- 2 identifiers
- labeling
- collection time
- collection time
- Avoid
- drawing around
IV line
- fluid/drugs
- fluid/drugs
- Excessive tourniquet time
- Hemoconcentration
- increased Ca
- Hemoconcentration
- Delay in
delivery to
lab
- drawing around
IV line
- cell lysis
- increased K and
Lactate
dehydrogenase
- increased K and
Lactate
dehydrogenase
- Special Handling and Storage
- ABG
- ABG
- patient ID
- Preparation
- add information to
pt database
- Diagnostic Test Characterisitcs
- Reference Interval
- REPORT
QUANTITATIVE
RESULTS
- Method and
laboratory
specific
- rep results
of 95% of
pop
presumed to
be healthy
- consider in
light of
patient
parameters
- REPORT
QUANTITATIVE
RESULTS
- Accuracy
- correspond to true value
- maximize
- calibrate equipment
- external
proficiency testing
- calibrate equipment
- correspond to true value
- Precision
- measure of
reproducibility when
repeated on same
sample
- IDEAL TEST IS BOTH
ACCURATE AND
PRECISE
- measure of
reproducibility when
repeated on same
sample
- Interfering factors
- considered in interpretation of
results
- external
- medications
- medications
- Internal
- abnormal
physiologic
states
- abnormal
physiologic
states
- external
- considered in interpretation of
results
- Sensitivity
- ability to detect disease
- 90% sensitive test gives
positive results in 90% of
diseased patients
- 10% of
diseased
patients will
get negative
results, aka
false negative
- high sensitivity
- useful to
exclude
diagnosis
- useful to
exclude
diagnosis
- 10% of
diseased
patients will
get negative
results, aka
false negative
- 90% sensitive test gives
positive results in 90% of
diseased patients
- % of patients w/ + test
for disease
- ability to detect disease
- specificity
- ability to
detect
absence
of a
disease
- ability to
detect
absence
of a
disease
- Reference Interval
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