Zusammenfassung der Ressource
2.7 DNA Replication, Transcription and Translation
- DNA Replication
- Nature of Science
- Evidence for scientific theories
- Meselson and Stahl
- Semi-conservative
replication of DNA
- Complementary
base pairing
- Helicase
- Unwinds the double helix and
separates the two strands by
breaking H bonds
- DNA Polymerase
- Links nucleotides together to
form a new strand, using
pre-existing strand as a template
- Polymerase chain reaction (PCR)
- Use of Taq DNA polymerase
to produce multiple copies
of DNA rapidly
- Transcription
- Synthesis of mRNA copied from the DNA
base sequences by RNA polymerase
- Translation
- Synthesis of polypetides
on ribosomes
- The amino acids sequence of
polypeptides is determined by
mRNA according to the genetic code
- Codons of three bases on
mRNA correspond to one
amino acid in a polypeptide
- Translation depends on complementary
base pairing between codons on mRNA
and anticodons on tRNA
- Use a table of the genetic
code to deduce which
codon corresponds to
which amino acid
- Deducing the DNA base
sequence for the mRNA strand
- Aim 8
- Ethical implications in altering
the genome of an organism in
order to produce proteins for
medical use in humans
- Production of human insulin in
bacteria as an example of the universal
versatility of the genetic code allowing
gene transfer between species