Zusammenfassung der Ressource
8.2 Cell Respiration
- Nature of Science
- Paradigm shift: the chemiosmotic theory led to
a paradigm shift in the field of bioenergetics
- TOK
- Peter Mitchell's chemisosmotic theory encountered
years of opposition before it was finally accepted
- For what reasons does falsification not always result in an
immediate acceptance of new theories or a paradigm shift
- Structure of
mitochondrion
- Electron tomography used to produce
images of active mitochondria
- Annotation of a diagram
of a mitochondrion
- Analysis of diagrams of the
pathways of aerobic respiration
- Redox reactions
- Oxidation
- Oil: Oxidation Is
Loss of electrons
- Reduction
- RIG: Reduction Is
Gain of electron
- Glycolysis
- Glucose is converted to
pyruvate in the cytoplasm
- Phosphorylation
- Lysis
- Oxidation
- Small net gain of ATP
- Link reaction
- Pyruvate
- Oxidative Decarboxylation
- H is removed
from pyruvate
- H is accepted by NAD+
giving NADH + H+
- CO2 production
- Pyruvate converted
into an acetyl group
- Acetyl group accepted
by coenzyme A (CoA)
- Acetyl CoA enters the
Krebs cycle
- Krebs cycle
- Oxidation of the acetyl groups
- Reduction of H carriers
- Decarboxylation
- Substrate level
phosphorylation
- ATP Formation
- Release of CO2
- NADH + H+ = NAD+
FADH2 + H+ = FAD
- Energy released by oxidation
reactionsis carreid to the cristae fo the
mitochondrai by reduced NAD+ and FAD
- Electron Transport Carriers (ETC)
- Transfer of electrons between carriers in the
electron transport chain in the membrane of the
cristae is coupled to proton pumping
- Oxidative phosphorylation =
Chemiosmosis
- Protons diffuse through ATP
synthase to generate ATP
- Oxygen is needed to bind with the free
protons to maintain the H gradient
- Water formation