Michael Jardine
Quiz von , erstellt am more than 1 year ago

PHSI3011 01-2 Cardiac excitation-contraction coupling 1 - Channels, exchangers, pumps

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Michael Jardine
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PHSI3011 01-2 Cardiac excitation-contraction coupling 1 - Channels, exchangers, pumps

PHSI3011 01-2 Cardiac excitation-contraction coupling 1 - Channels, exchangers, pumps

Frage 1 von 6

1

Which of the following is NOT a type of Calcium channel?

Wähle eine der folgenden:

  • G-type

  • L-type

  • N-type

  • T-type

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Frage 2 von 6

1

An L-type Calcium channel has how many subunits?
(each controlled by a separate gene)

Wähle eine der folgenden:

  • 2

  • 3

  • 4

  • 5

  • 6

  • 7

  • 8

Erklärung

Frage 3 von 6

1

An L-type Calcium channel is highly selective for Calcium, but is also somewhat permeable to Sodium and Potassium.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 4 von 6

2

During diastole, the Na/Ca exchanger and the SR Ca pump both move Ca. Which way around?

Wähle eine der folgenden:

  • Na/Ca exchanger will pull Ca IN to the myoplasm; the SR Ca pump will pump Ca back INTO the SR.

  • Na/Ca exchanger will pull Ca IN to the myoplasm; the SR Ca pump will pump Ca back OUT of the SR.

  • Na/Ca exchanger will push Ca OUT from the myoplasm; the SR Ca pump will pump Ca back INTO the SR.

  • Na/Ca exchanger will push Ca OUT from the myoplasm; the SR Ca pump will pump Ca back OUT of the SR.

Erklärung

Frage 5 von 6

3

Wähle von der Dropdown-Liste, um den Text zu vervollständigen.

The longitudinal SR contains a high concentrations of proteins acting as an ATP-dependent Ca pump - returning Ca from the myoplasm to the SR lumen (to help terminate contraction).
These proteins are called SERCA.
What does SERCA stand for?
( Sarco, Sarcoplasmic ) ( Endo, Endoplasmic ) ( [plasmic] Reticulum, [plasmic] Ryanodine ) ( Calcium, Concentration ) ( Activation, Activator, Adjustment, ATPase )

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Frage 6 von 6

1

The role that Phospholamban plays in regulation of the SR Ca pump is:

Wähle eine der folgenden:

  • Inhibitory; cancelled when phosphorylated.

  • Inhibitory; reinforced when phosphorylated.

  • Permissive; cancelled when phosphorylated.

  • Permissive; reinforced when phosphorylated.

Erklärung

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