PHSI3011 02-1 Cardiac excitation-contraction coupling 2 - How to vary contraction of the heart

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Unlike Skeletal muscle, cardiac muscle always recruits every cardiac muscle cell for every contraction. Consequently, contraction force can't be changed by recruiting different numbers of cells for each Compound Action Potential.
So... instead, contractile force is varied using .

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Binding of Ca to troponin causes movement of tropomyosin so it no longer blocks active site on actin.
Binding of Ca to tropomyosin causes movement of troponin so it no longer blocks active site on actin.
Binding of Ca to troponin causes movement of actin so it no longer blocks active site on tropomyosin.
Binding of Ca to tropomyosin causes movement of actin so it no longer blocks active site on troponin.
Binding of Ca to actin causes movement of tropomyosin so it no longer blocks active site on troponin.
Binding of Ca to actin causes movement of troponin so it no longer blocks active site on tropomyosin.

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	Erstellt von Michael Jardine vor etwa 7 Jahre