Lecture 3 solubility and dissolution 1

What is a solution

if a drug is dissolved in water, which s the solute and which is the solvent?

besides solid in water, what other types of solutions exist?

What are the three steps in dissolution of solid in liquid?

What is a saturated solution?

what is a supersaturated solution?

True or False
if the solute-solvent forces are strong enough to compensate for the forces that are broken, then it is likely that the solid will dissolve in a solvent

True or False
The overall heat exchanged in dissolution process is called entropy

What effect will heating the solvent have on dissolution of a drug which has a negative heat of solution?

What effect will heating solvent have when a drug has a positive heat of solution?

True or False
If a drug dissolving in solvent has negative heat of solution, we have an endothermic process

What is the dielectric constant

Which of the following solvents will have the highest dielectric constant:
water
alcohol
benzene

If we have a polar drug, which solvent will it best dissolve in?
water or benzene

Alcohol has a lower dielectric constant than water and is classed as semi-polar solvent
True or False

Write the Noyes-Whitney equation (used to describe rate of dissolution)