The National Competent Authority BfArM is responsible for: (more than one answer is correct)
approval of substances
approval of studies on medicial devices
approval of studies on pharmaceuticals
inspection of study sites
inspections of animal space
approval of genetic studies
The primary outcome of a First-in-Human study is always:
Safety and tolerability
Feasibility
Pharmacodynamics
Therapeutic effect
What is the main advantage of bipolar electrophysiological recordings, compared to a common reference?
better spectral resolution
better time resolution
better spatial resolution
higher amplification
Which answer is wrong? The core features of schizophrenia include:
Cognitive dysfunction
Delusions and paranoia
Social withdrawal
Inflated sense of self importance
Depressive episodes
The following are effective treatments for schizophrenia: (more than one answer might be correct)
antipsychotic medication
stimulate medication
cognitive behavior therapy (CBT)
social skill training
ECT
Question 6 Which of the following statements is true?
The hyperdirect pathway involves the primary motor cortex and the subthalamic nucleus.
The direct pathway is from the primary motor cortex directly to the GPi
The main neurotransmitter of medium spiny neurons is glutamate.
Dopamine is mainly produced in the substantia nigra pars reticulata.
Striatal interneurons account for more than 90% of all striatal neurons.
Schizophrenia is a genetic disorder,
but it is not heritable.
and its heritability is around 80%.
and environmental factors are not important.
and its heritability is around 10%.
but genetics factors are not associated with schizophrenia symptoms.
Which of these anatomic structures is not part of the basal ganglia?
Corpus striatum
Red nucleus
Subthalamic nucleus
Caudate nucleus
Which brain function is dominated most by one hemisphere?
Hearing
Language
Vision
Memory
Smelling
Which study(ies) belong(s) to Phase I? (more than one answer might be correct)
Bioequivalence
First in Human
Pharmacokinetics in renal impairment
Proof of concept
Pharmacokinetic drug interaction
