In 2011, 62.8% of Australians over 18yo were __________.
Obese
Overweight
Obese OR Overweight
[none of the above]
Which of the following can go along with obesity?
Cardiovascular disease
Cancer
Insulin resistance
Sleep apnoea
Asthma
Alzheimer’s
T2D
Infertility
Anorexia
T1D
The average energy expenditure is roughly 1,000 2,500 6,000 20,000( 1,000, 2,500, 6,000, 20,000 ) kcal/day.
Does Ghrelin stimulate or suppress hunger/feeding?
Stimulate
Suppress
Does Peptide YY (PYY) induce hunger or satiety?
Satiety
Hunger
Leptin downregulates the production of appetite--stimulating -suppressing( -stimulating, -suppressing ) neuropeptides.
Does Insulin push you towards hunger or satiety?
Environmental- vs Genetic- determinants of obesity. ❌ accounts for ~30-40%; ❌ accounts for ~60-70%.
Adoption studies suggest a stronger role for ❌ than ❌ in predicting future weight.
Which of the following two single-gene-defects could cause Rapid weight gain, Hyperplasia?
Leptin (LEP)
Leptin receptor (LEPR)
MelanoCortin-4 Receptor (MC4R)
Which of the following is the most common single-gene cause of obesity? (it’s only present in 2-5% of persons with severe obesity, though!)
There are shitloads of genes associated with obesity. Broadly 4 categories (Monogenic oligogenic; Fat distribution-related; BMI-related genes; Overweight, Obesity-related). Treating them as a Venn diagram, what’s the only one in the overlap of all 4?
MC4R
LEPR
TUB
LEP
Gastric banding results in a mean weight reduction of 15-20% ~25% ~30%( 15-20%, ~25%, ~30% ) at 1 year.
Vertical-sleeve Gastrectomy results in what mean % weight reduction at 1 year?
15-20%
~25%
~30%
Roux-en-Y Gastric Bypass (RNY) results in what mean % weight reduction at 1 year?
