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sterile sites of human body
Human Microbiome Project
conclusions of human microbiome project
How might different microbial communities perform the same functions at a given site?
How to compare two colonies from two different individuals
What areas of the skin can microbes occupy?
different skin environments
P. acnes
oral cavity microenvironments: below the gum line
oral cavity microenvironments: above the gum line
What happens with poor oral hygiene?
Stages of enamel decay
Microbiome of vaginally born babies vs Cesarean section
microbiome pH going down the human gut
alpha diversity
beta diversity
in general, what AFFECTS the GI microbiome?
in general, what is the EFFECT of the GI microbiome?
How do we tolerate billions of commensals?
Experimental evidence of gut microbiome's important role in the immune system
TH17 cells vs Treg cells in segmented filamentous bacteria (SFB)
Gut microbiome link to obesity/metabolic disease: antibiotics and weight gain
Gut microbiome link to metabolic disease: H. pylori and hormones
CHO diet effect on microbiome
(diet --> GI)
Microbiome effect on fat accumulation
(GI --> body)
disbiosis
gnotobiotic mice
Bacteriodes fragillis and Clostridiae in Human Microbiome
effect of human fecal transplant on GF mice
results of cohousing mice with "lean" microbiota and "obese" microbiota (fed on same diet)
results of cohousing mice with "lean" microbiota and "obese" microbiota (fed on different diets)
signaling pathways that most affect metabolic outcomes
What happens when you disturb the GI ecosystem?
treatments for recalcitrant C. difficile
probiotics effect on health
