DNA VI - Translation and the Ribosome

Define a Ribosome -

Describe the functions of a ribosome

How does a ribosome facilitate tRNA binding?

What are ribosomes composed of?

How is the size of a ribosome measured?

What are the subunits of a ribosome?

Draw a diagram of an E. Coli cell ribosome.

Human ribosome

How do mitochondrial ribosomes differ to human ribosomes

Draw a diagram showing the process of translation

Describe very briefly this translation

What is the first amino acid encoded in prokaryotes?

Describe the process of initiation in E.Coli

What is this sequence known as?

Describe the binding of the tRNA molecule to the ribosome

Draw a diagram showing this binding

Describe translation initiation in Eukaryotes

How does the ribosome bind to the mRNA molecule?

Draw a diagram you cunt

Draw a diagram translation elogation

What does the elongation cycle consist of?

What is the result of each cycle?

What terminates a cycle?

Why does a stop codon terminate a cycle?

What is the energy expenditure during translation?

What is each molecule equivalent of ATP used for?

Peptidyl transferase diagram. Cunt.

What component of the ribosome catalyses the peptidyl-transferase reaction in E.Coli?

How do we know this?

What are elongation factors?

Name the elongation factors required for prokaryotic elongation and its eukaryotic equivalent

Describe Step 1 of Elongation

Describe Step 2 of Elongation

Compare eukaryotic and prokaryotic ribosomes

Name and describe the effects of a class of antibiotics that effect ribosomes

Name and describe the effects of a class of antibiotics that effect ribosomes cont.

Name and describe the effects of a class of antibiotics that effect ribosomes (Cont. cont.)