Antipsychotics

What is the prime driver in lack of treatment adherence in schizophrenia

Which receptor makes antipsychotic an atypical antipsychotic

What is the black box warning for atypical antipsychotics

What is the biggest concern in the use of atypical antipsychotic ClozaPINE (Clozaril)

How often should a patient on ClozaPINE (Clozaril) be monitored

What is the main concern with OlazaPINE (Zyprexa)?

What is contraindication/concern for QuetiaPINE (Seroquel)?

What makes AsenaPINE (Saphris) MOA unique?

What is the CI/concern with AsenaPINE (Saphris)

Which atypical antipsychotic can be used for autism irritability

Which atypical antipsychotic can also be used as a mood stabilizer

Which atypical antipsychotic can increase prolactin levels even at low doses

What makes the administration of Paliperidone (Invega) unique

Contraindications/Concerns for Paliperidone (Invega) include risk of

What is the biggest concern/adverse effect to monitor with ZiprasiDONE (Geodon)

Which medication lowers the risk of EPS

What reduces the metabolic risk in Larisidone and makes it less sedating?

Which of the following is a third generation antipsychotic whose MOA is DA partial agonist?

When is weight gain most important with atypical antipsychotics

Rick has a history of schizophrenia and has been very non-adherent in the past. He has been on several medications in the past, including aripiprazole (ineffective), haloperidol (EPS), quetiapine (sedation), risperidone (effective) and ziprasidone (ineffective). His PMHNP would like to start him on a long-acting injectable to help increase his adherence. Rick would receive the injection at his monthly doctor's appointment, immediately prior to his appointment. Given this information, which of the following medications would the best potential agent for Rick?

Fred, your patient with Schizophrenia, is having an involuntary muscle contraction that pulls his head drastically to the left side. It is very uncomfortable. You know that medications to treat schizophrenia can cause side effects and given his presentation and discomfort, which side effect is he experiencing?

A 34 y/o female with schizophrenia is not responding to a standard dose of an antipsychotic. Which of the following might you suspect?

Sally is a 32 year old female treated for schizoaffective disorder, bipolar type. She is treated with Invega (paliperidone) 12 mg po daily. Sally reports she has not had her menses in over 6 months and complains of galactorrhea. You know this is due to prolactin elevation through which dopamine pathway?

Sammy is a 56 y/o patient who has been taking an atypical antipsychotic for six months. She has experienced a 22 lb weight gain since starting this agent. Which of the following pharmacologic properties most likely underlies this patient's weight change?

Charles is a 34-year-old male treated for schizophrenia and has been stable on invega trinza 819 mg IM every three months. Charles has a long history of psychiatric hospitalizations and this is the first time since his diagnosis at age 22 that he has not hospitalized in over three years. Charles is presenting as a new patient to your clinic, and part of the initial evaluation you order laboratory studies that reveal the following:
Triglycerides 388 mg / dL, LDL 180 mg / dL, Hemoglobin A1C 8, WBC 8.8 cells / mcL, and Prolactin level 67 ng/ML. As the PMH NP treating Charles what is a reasonable next step?

Doris is a 44-year-old female treated for schizophrenia and has been stable on clozapine 300 mg po HS. The only side effect she has is sialorrhea, which she copes with by putting a towel on her pillow. At the day treatment center she has been part of a research study focused on tobacco cessation. Doris was smoking 2 ppd and is now down to less than 10 cigarettes a day. At her follow up visit, she presents sedated, confused, and her blood pressure is 80/60 mmHg, radial pulse 110. What is your appropriate next step?

Which of the following antipsychotic medication is least likely to cause orthostatic hypotension?

A 24 year old man with schizophrenia was stable on aripiprazole. Two weeks ago he saw his PCP for night sweats, weight loss, fatigue and cough. He had a positive purified protein derivative (PPD) and chest X ray. He is starting on isonicotinylhydrazine (INH) and rifampicin today. You suspect a drug interaction, what is your next step?

Mr. Smith is a 45 year old patient with schizophrenia recently discharged from the state psychiatric hospital. This is Mr. Smith's forth hospitalization in the last 9 months. He was discharged on Haldol 10 mg po daily and Divalproex Sodium 500 mg at HS. Due to his history of medication nonadherence, you talk about long acting injectable medication and he agrees. What is the most appropriate starting dose of haloperidol decanoate?

Which of the following is cited as the most common reason persons with schizophrenia stop taking medications?

Which of the following statements best describes the difference between high and low potency antipsychotic medications?

Mr. Mac is taking haloperidol (Haldol) deaconate 100 mg IM every 4 weeks for the treatment of schizoaffective disorder. Knowing what you know about high and low potency antipsychotics, which side effects is he more likely to experience?

When an atypical antipsychotic is said to have lost it's atypicality, it is referring to which of the following?

What is unique properties does clozapine have, when compared to all other atypical antipsychotic medication?