The limbic system is an integrative separate equilizing( integrative, separate, equilizing ) system that utilizes information from and has complex connections with, many different subsystems (motor, sensory, and autonomic systems).

limbic lobe was identified as consisting of a ring-like area of cortex on the medial surface of each cerebral hemisphere, including the cingulate gyrus, parahippocampal gyrus and septal cortex – all three of which are interconnected by a white matter pathway called the cingulum striatum mesolimbic pathway( cingulum, striatum, mesolimbic pathway )

Explicit Implicit( Explicit, Implicit ) memory refers to the conscious recollection of facts
Explicit Implicit( Explicit, Implicit ) memory refers to the subconscious learning of skills, habits or behaviors

Severe memory deficit is usually observed only when the damage is bilateral unilateral( bilateral, unilateral )

When lesions/damage create issues in the consolidation process of placing short-term memories into long-term storage this is referred to as anterograde retrograde( anterograde, retrograde ) amnesia while anterograde retrograde( anterograde, retrograde ) amnesia refers to the loss of previously formed long-term memories.

Prefrontal cortex:
Dorsolateral Ventomedial Orbitofrontal cortex (OFC) Anterior cingulate cortex (ACC)( Dorsolateral, Ventomedial, Orbitofrontal cortex (OFC), Anterior cingulate cortex (ACC) ) = executive, problem solving and analyzing
Ventomedial Dorsolateral Orbitofrontal cortex (OFC) Anterior cingulate cortex (ACC)( Ventomedial, Dorsolateral, Orbitofrontal cortex (OFC), Anterior cingulate cortex (ACC) ) = role in emotional processing
Orbitofrontal cortex (OFC) Dorsolateral Ventomedial Anterior cingulate cortex (ACC)( Orbitofrontal cortex (OFC), Dorsolateral, Ventomedial, Anterior cingulate cortex (ACC) ) = regulate impulses, compulsions, and drives
Anterior cingulate cortex (ACC) Dorsolateral Ventomedial Orbitofrona( Anterior cingulate cortex (ACC), Dorsolateral, Ventomedial, Orbitofrona ) = selective attention, emotions, depression, and anxiety

Mood Temperament( Mood, Temperament ) is an internal subjective state that fluctuates in response to physiological and environmental circumstances
Mood Temperament( Mood, Temperament ) refers to the relatively stable characteristics and personality traits of individuals and how they engage with the world throughout their lifetime

Glutamate GABA Endocannabinoids Serotonin Noradrenaline Dopamine Acetylcholine( Glutamate, GABA, Endocannabinoids, Serotonin, Noradrenaline, Dopamine, Acetylcholine ) = turns brain on; builds memory; regulates awareness, movement, sensation & mood
GABA Glutamate Endocannabinoids Serotonin Noradrenaline Dopamine Acetylcholine( GABA, Glutamate, Endocannabinoids, Serotonin, Noradrenaline, Dopamine, Acetylcholine ) - turns brain off; involved in sleep, sedation, relaxation, reducing anxiety & decreasing muscle tension
Endocannabinoids Glutamate GABA Serotonin Noradrenaline Dopamine Acetylcholine( Endocannabinoids, Glutamate, GABA, Serotonin, Noradrenaline, Dopamine, Acetylcholine ) = regulate pain, appetite
Serotonin Glutamate GABA Endocannabinoids Noradrenaline Dopamine Acetylchonie( Serotonin, Glutamate, GABA, Endocannabinoids, Noradrenaline, Dopamine, Acetylchonie ) = regulate mood, anxiety, appetite, sleep cycle
Noradrenaline Glutamate GABA Endocannabinoids Serotonin Dopamine Acetylcholine( Noradrenaline, Glutamate, GABA, Endocannabinoids, Serotonin, Dopamine, Acetylcholine ) = feelings of alertness, attention, concentration, raising BP, lifts mood, can cause anxiety
Dopamine Glutamate GABA Endocannabinoids Serotonin Noradrenaline Acetyhlcholine( Dopamine, Glutamate, GABA, Endocannabinoids, Serotonin, Noradrenaline, Acetyhlcholine ) = creates feelings of motivation and drive, liking, attention, pleasure & enjoyment in food
Acetylcholine Glutamate GABA Endocannabinoids Serotonin Noradrenaline Dopamine( Acetylcholine, Glutamate, GABA, Endocannabinoids, Serotonin, Noradrenaline, Dopamine ) = regulates sleep cycle and alertness and builds memory

Mesolimbic pathway Mesocortical pathway( Mesolimbic pathway, Mesocortical pathway ) (VTA nucleus accumbens and other limbic system structures such as the amygdala) – involved in pleasure and reward; stimulation of this pathway results in a sense of pleasure.
Mesolimbic pathway Mesocortical pathway( Mesolimbic pathway, Mesocortical pathway ) (VTA prefrontal cortex) – involved in motivational behavior; tied to pleasure and reward.

Glutamate is the most least( most, least ) used neurotransmitter in the nervous system and is always never( always, never ) thought to cause an excitatory postsynaptic response.