which microorganisms that the commercial production of biosynthetic penicillins today depend on various strains

structure of penicillin

gram-negative bacilli is resistant to ____?

enzyme that inactivates penicillins

two general types of the enzyme that inactivates penicillins

another name of Pen G

it is an agent of choice for the tx of more different kinds of bacterial infection than any other antibiotic

K, Ca and Na salts are inactivated by _______

amine sale of penicillin G was made with _______

preparation of Pen G Procaine

it is a salt of diamine

composition of the diamine

another name of Pen V

Pen V is resistant to hydrolysis by ________________ and its ability to produce uniform concentration in ____________

Methicillin sodium is particularly resistant to inactivation by the ___________ found in _________ and somewhat more resistant than __________ to penicillinase from ________________.

it is used in the treatment of staphylococcal infections caused by strains resistant to other penicillins

Explain: resistant to inactivation by the penicillinase

it is highly resistant to inactivation by penicillinase

chlorine atom ortho to the position of attachment of the phenyl ring to the isozaxole ring enhances the activity of __________________ ____________

dicloxacin sodium

nafcillin is stable enough in _______ to perming its use by _______ administration

another semisynthetic penicillin that resulted from the search for penicillinase-resistant compounds

Nafcillin sodium may be used in infections caused solely by ___________ __________ ______________ or when _______________ are present also.

its antibacterial spectrum is broader than that of penicillin G

It is particularly useful for the treat- ment of acute urinary tract infections caused by _____ or ___________ and is the agent of choice against _________ infections.

ampicillin + ________ = tx for gonorrhea

It is a prodrug of ampicillin with no antibacterial activity

hydrolyzed rapidly by _____

it has largely replaced ampicillin for the treatment of certain _____ and__________ for which oral administration is desirable

it has a broad range of antimicrobial activity, broader than any other known penicillin

provides an orally active alternative for the treatment of _________ and _______ caused by Pseudomonas spp., indole-positive Proteus spp., and se- lected species of Gram-negative bacilli.

advantages of ticarcillin

an acylureidopenicillin

It is more active than mezlocillin against susceptible strains of Gram-negative aerobic bacilli, such as Serratia marcescens, Proteus, Enterobacter, Citrobacter spp., and P . aeruginosa

ex- tended-spectrum acylureidopenicillins