Chapter 15

innate defense (specific or nonspecific?)

adaptive defense (specific or nonspecific?)

"non self" molecules

Ag: usually large and ___ to the body

___ immunity: uses___ produced by the B cells

___-____ immunity: uses T cells

activation of innate immunity triggered by ____

LPS from gram ____ bacteria cell membrane

_____ from gram positive bacteria cell wall

How do immune cells recognize PAMPs?

PAMP-TLR complex eventually leads to ___

inflammation initiates ____ phagocytosis by blood phagocytes

4 main characteristics of inflammation

to initiate inflammation, cytokines activate ___ cells near the damaged area

mast cells release ____ which ____ blood vessels and ___ cell membrane permeability

another word for extravasation

chemotaxis: recruits _____ (in the blood) which become ____ in the tissue

cytokines induce _____ of bronchi and bronchioles for protection

Phagocytosis: degradation of bacteria by ___

tissue damage--> expressed _____--> leads to ____-->inflammation

macrophages responsible for pus formation

order of phagocytes to arrive at site of infection

body temperature regulated by the ___

3 ways to induce fever

3 effects of fever

interferons are ____ produced by cells with a ___ that offer short-term, ____ resistance to viral infection

main effect of interferons

B cells: named after ___ of Fabricius

b cells= ____ cells and plasma cells

t cells= of ___ origin

HIV virus attacks _____ t cells

B cells= Ab _____

expansion of B cell ___->progeny become memory or plasma cells

___ cells=factory

Ab structure:
2 ___ chains and 2 ____ chains
each chain contains ___ (Fc) and ___ (Fab) fragments

3 Ab classifications

3 main T-cells

Killer (____) T cells: secrete ____ (leads to lysis) and _____(destroys victim's DNA)

Helper T cells: increase responses of ___ and ____ cells

Suppressor T cells: protect against ____ responses