Neuromuscular Blockade

Frage 1 von 16

1

Use of succinylcholine to facilitate endotracheal intubation would be acceptable (“safe”) in which one of the following situations:

Wähle eine der folgenden:

80 y.o. female patient 2 days after 40% body surface area burn
18 y. o. male one week after spinal cord transection injury
12 y.o. with Duchene’s muscular dystrophy
22 y. o. with evolving respiratory failure secondary to Guillian-Barre’
27 y. o. female with myasthenia gravis

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Frage 2 von 16

1

A patient taking which of the following drugs would most commonly be associated with resistance to (nondepolarizing) NMB drugs:

Wähle eine der folgenden:

Quinidine
Phenytoin
Cyclophosphamide
Aminoglycosides
Magnesium

Erklärung

Frage 3 von 16

1

The MOST important parameter that determines the speed of onset for NMB drugs is:

Wähle eine der folgenden:

Potency
Lipophilicity
Ionization
Plasma clearance
E. Receptor affinity

Erklärung

Frage 4 von 16

1

A characteristic common to current aminosteroid-based NMB drugs such as vecuronium or rocuronium is:

Wähle eine der folgenden:

Significant histamine release after a bolus injection
Vagolysis producing tachycardia
Hofmann elimination
Deacetylation in the liver
Production of laudanosine as the primary metabolite

Erklärung

Frage 5 von 16

1

Wähle von der Aufklappliste, um den Text zu vervollständigen.

Clinical data support that when the TOFR exceeds ( 0.4, 0.2, 0.7, 0.9 ),
anesthesia providers have trouble assessing the presence
of fade

Erklärung

Frage 6 von 16

1

Wähle von der Aufklappliste, um den Text zu vervollständigen.

TOF count of 3 would equate to a twitch suppression of ( 55, 75, 85, 90 )%

Erklärung

Frage 7 von 16

1

Wähle von der Aufklappliste, um den Text zu vervollständigen.

Once the TOF ratio exceeds ( 0.60, 0.40, 0.70, 0.85 ), fade to DBS generally cannot be detected subjectively

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Frage 8 von 16

1

What is true about Tetanic stimulation (TET)?

Wähle eine der folgenden:

During partial depolarizing block, fade is not observed in response to tetanic stimulation
Tetanic stimulation is not painful
Muscular fatigue usually develop at a stimulation frequency of 50 Hz
Fade is thought to be an effect of a depolarizing agent on the presynaptic nerve membrane

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Frage 9 von 16

1

Which statement about posttetanic count is NOT correct?

Wähle eine der folgenden:

The number of posttetanic count twitches is inversely related to time until the first regular TOF twitch returns
Posttetanic count used when TOF or DBS is absent to estimate recovery time
Posttetanic count uses tetany followed by TOF at frequency of 1 Hz
The main use of posttetanic count is when profound neuromuscular block is not required

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Frage 10 von 16

1

Correct statements about objective monitoring techniques include:

Wähle eine der folgenden:

Mechanomyography (MMG) measures isotonic contraction of peripheral muscles in response to nerve stimulation
Acceleromyography (AMG) calculates the force of contraction of a muscle using a miniature piezoelectric transducer
Electromyography (EMG) measures the electrical activity (compound muscle action potential) of a stimulated muscle
Kinemyography (KMG) detects the acceleration of the thumb contraction in response to electrical stimulation of a nerve

Erklärung

Frage 11 von 16

1

All of the following are examples of Benzylisoquinolinium compounds consist of two quaternary ammonium groups joined by methyl groups EXCEPT:

Wähle eine der folgenden:

D-tubocurarine
Atracurium
Mivacurium
Pancuronium
Cisatracurium

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Frage 12 von 16

1

Train-of-four (TOF) has all of the following characteristics, EXCEPT:

Wähle eine der folgenden:

TOF consists of four ST stimuli at a frequency of 4 Hz
TOF does not require a “baseline” or “control” muscle response
TOF “fade” is defined as a weaker fourth twitch than the first twitch
TOF is delivered every 15-20 sec to prevent potentiation of subsequent responses
TOF ratios >0.40 cannot be reliably detected subjectively (visually or tactilely)

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Frage 13 von 16

1

Double burst stimulation (DBS) characteristics include all of the following, EXCEPT:

Wähle eine der folgenden:

The two mini-tetanic bursts are separated by 0.5 sec
DBS is delivered no more frequently than every 20 sec to prevent subsequent response potentiation
In DBS, similar to TOF pattern, no control (“baseline”) muscle response is needed
DBS ratios >0.60 cannot be reliably detected by subjective (tactile, visual) means
In awakening patients, DBS is more painful than TOF, but less so than tetanic stimulation

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Frage 14 von 16

1

Potential side-effects associated with the use of succinylcholine include all of the below, EXCEPT:

Wähle eine der folgenden:

Myalgia
Tachycardia
Anaphylaxis
Hyperkalemia

Erklärung

Frage 15 von 16

1

Since sugammadex has no direct cholinergic properties, anesthesiologist do not require the ready availability of an anticholinergic like glycopyrrolate at the time of reversal.

Wähle eins der folgenden:

WAHR
FALSCH

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Frage 16 von 16

1

When administering sugammadex through a peripheral IV, it is important to note that the drug has a physical incompatibility with all of the following drugs except:

Wähle eine der folgenden:

Verapamil
Dexamethasone
Ranitidine
Odansetron

	Erstellt von Mike Ru vor etwa 6 Jahre

Diplomat of ABA Medicine (Fundamental Topics in Anesthesiology) Quiz am Neuromuscular Blockade, erstellt von Mike Ru am 28/04/2018.

Neuromuscular Blockade

Neuromuscular Blockade

Frage 1 von 16

Use of succinylcholine to facilitate endotracheal intubation would be acceptable (“safe”) in which one of the following situations:

Wähle eine der folgenden:

Erklärung

Frage 2 von 16

A patient taking which of the following drugs would most commonly be associated with resistance to (nondepolarizing) NMB drugs:

Wähle eine der folgenden:

Erklärung

Frage 3 von 16

The MOST important parameter that determines the speed of onset for NMB drugs is:

Wähle eine der folgenden:

Erklärung

Frage 4 von 16

A characteristic common to current aminosteroid-based NMB drugs such as vecuronium or rocuronium is:

Wähle eine der folgenden:

Erklärung

Frage 5 von 16

Wähle von der Aufklappliste, um den Text zu vervollständigen.

Clinical data support that when the TOFR exceeds 0.4 0.2 0.7 0.9( 0.4, 0.2, 0.7, 0.9 ), anesthesia providers have trouble assessing the presence of fade

Erklärung

Frage 6 von 16

Wähle von der Aufklappliste, um den Text zu vervollständigen.

TOF count of 3 would equate to a twitch suppression of 55 75 85 90( 55, 75, 85, 90 )%

Erklärung

Frage 7 von 16

Wähle von der Aufklappliste, um den Text zu vervollständigen.

Once the TOF ratio exceeds 0.60 0.40 0.70 0.85( 0.60, 0.40, 0.70, 0.85 ), fade to DBS generally cannot be detected subjectively

Erklärung

Frage 8 von 16

What is true about Tetanic stimulation (TET)?

Wähle eine der folgenden:

Erklärung

Frage 9 von 16

Which statement about posttetanic count is NOT correct?

Wähle eine der folgenden:

Erklärung

Frage 10 von 16

Correct statements about objective monitoring techniques include:

Wähle eine der folgenden:

Erklärung

Frage 11 von 16

All of the following are examples of Benzylisoquinolinium compounds consist of two quaternary ammonium groups joined by methyl groups EXCEPT:

Wähle eine der folgenden:

Erklärung

Frage 12 von 16

Train-of-four (TOF) has all of the following characteristics, EXCEPT:

Wähle eine der folgenden:

Erklärung

Frage 13 von 16

Double burst stimulation (DBS) characteristics include all of the following, EXCEPT:

Wähle eine der folgenden:

Erklärung

Frage 14 von 16

Potential side-effects associated with the use of succinylcholine include all of the below, EXCEPT:

Wähle eine der folgenden:

Erklärung

Frage 15 von 16

Since sugammadex has no direct cholinergic properties, anesthesiologist do not require the ready availability of an anticholinergic like glycopyrrolate at the time of reversal.

Wähle eins der folgenden:

Erklärung

Frage 16 von 16

When administering sugammadex through a peripheral IV, it is important to note that the drug has a physical incompatibility with all of the following drugs except:

Wähle eine der folgenden:

Erklärung

Clinical data support that when the TOFR exceeds ( 0.4, 0.2, 0.7, 0.9 ),
anesthesia providers have trouble assessing the presence
of fade

TOF count of 3 would equate to a twitch suppression of ( 55, 75, 85, 90 )%

Once the TOF ratio exceeds ( 0.60, 0.40, 0.70, 0.85 ), fade to DBS generally cannot be detected subjectively