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Which of the following is an inherited disorder of bilirubin metabolism?
All answers are correct
Crigler-Najjar syndrome
Gilbert’s disease
Dubin-Johnson syndrome
Which of the following enzymes would be raised in serum from a patient with hepatocellular disease?
Creatine kinase
Lactate dehydrogenase
Alanine amino transerferase
Ferroxidase
Which of the following is the major liver metabolite of bilirubin
stercobilin
bilirubin monoglucuronide
unconjugated bilirubin bilirubin diglucuronide
bilirubin diglucuronide
Which of the following does not cause chronic liver disease?
Hepatitis A
Hepatitis C
Chronic high alcohol ingestion
Hepatitis B
none of them
Which of the following best defines jaundice?
Yellow discolouration of the skin or sclera of the eye, due to increased bilirubin in plasma >40umol/l Low serum bilirubin concentration
Increased bilirubin in plasma >40umol/l
Brain damage due to high bilirubin concentrations
Low serum bilirubin concentration
Which of the following can arise as a result of acute hepatic failure?
Acid-base disturbance
Hypoglycaemia
Electrolyte imbalance
Which of the following can be a cause of acute liver disease?
Heart failure leading to inadequate liver perfusion
Paracetamol poisoning
Which is found in haemolytic jaundice?
Increased serum haptoglobins
Low serum unconjugated bilirubin
Pale stools due to decreased bilirubin metabolites
High serum unconjugated bilirubin
Which of the following can cause liver cirrhosis?
Chronic hepatitis B infection
Anti-mitochondrial antibodies
Which is found in obstructive jaundice?
High serum conjugated bilirubin
Dark stools due to increased bilirubin metabolites
Increased serum haptoglobin
