Physiology III: Excitatory and Inhibitory Neurotransmission in the CNS

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There is a higher concentration of ( sodium, potassium ) on the outside of the cell and ( potassium, sodium ) inside the cell

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The is a significantly ( higher, lower ) concentration of Calcium extracellularly.

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Na flows inwards, causing ( depolarisation, hyperpolarisation ) which is ( excitatory, inhibitory )
Ca flows inwards, causing ( depolarisation, hyperpolarisation ) which is ( excitatory, inhibitory )
Cl flows inwards, causing ( hyperpolarisation, depolarisation ) which is ( inhibitory, excitatory )
K flows outwards, causing ( hyperpolarisation, depolarisation ) which is ( inhibitory, excitatory )

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Frage 4 von 20

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Based on the previous question, will a drug that acts as a Na channel antagonist be excitatory or inhibitory?
( Inhibitory, Excitatory, Neither )

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Frage 5 von 20

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Based on the previous question, will a drug that acts as a Potassium channel antagonist be excitatory or inhibitory?
( Excitatory, Inhibitory )

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Frage 6 von 20

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Events at the Synapse are mostly mediated by means of ..

Wähle eine der folgenden:

Calcium Channels
Sodium Channels
Potassium Channels
Chlorine Channels

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Frage 7 von 20

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There are two types of receptors upon which neurotransmitters can act.
❌: Direct gating, whereby the receptor is an integral part of the channel it controls
❌: Indirect gating, whereby the receptor and the channel it controls are distinct from one another.

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Ionotropic Receptor

Metabotropic Receptor

Synapotropic Receptor

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Frage 8 von 20

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Label the receptor types shown in the diagram below.

Ziehe eine Antwort zum richtigen orangen Punkt.

Ionotropic Receptors

Synapotropic Receptors

Metabotropic Receptors

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Frage 9 von 20

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The major excitatory neurotransmitter is ...

Wähle eine der folgenden:

GABA
Glutamate
Glycine
Dopamine

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Frage 10 von 20

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However, Glutamate can sometimes also elicit inhibitory effects via ( metabotropic, ionotropic ) glutamate receptors

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Frage 11 von 20

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Ionotropic Glutamate Receptors:
NMDA receptors mediate ( slow, fast ) excitatory synaptic transmission in the CNS
Non-NMDA receptors mediate ( fast, slow ) excitatory synaptic transmission in the CNS

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Frage 12 von 20

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The major inhibitory neurotransmitter is ...

Wähle eine der folgenden:

Glutamine
GABA
Glycine
Dopamine

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Frage 13 von 20

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As GABA is an inhibitory Neurotransmitter, it tends to mediate which of the following ions.
( Potassium & Chlorine, Potassium & Sodium, Sodium & Chlorine, Sodium & Calcium )

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Frage 14 von 20

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Ionotropic GABA receptors tend to mediate ( Chlorine channels, Potassium channels )
Metabotropic GABA receptors tend to mediate ( Potassium channels, Chlorine channels )

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Frage 15 von 20

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❌ Receptors are faster and act simply as 'on-off' switches for channels

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Ionotropic

Metabotropic

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Frage 16 von 20

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❌): Depolarising change in resting membrane potential caused by actions of neurotransmitters.
❌): Hyperpolarising change change in resting potential caused by actions of neurotransmitters.

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Excitatory Post-Synaptic Potential (EPSP

Inhibitory Post-Synaptic Potential (IPSP

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Frage 17 von 20

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A change in resting membrane potential caused by EPSP or IPSP that is not of sufficient magnitude to cross the threshold for an action potential is called ...

Wähle eine der folgenden:

An Almost There Potential
A Graded Potential
A Median Potential
A Charted Potential

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Which neurotransmitter are excitatory neurons most likely to release?

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Frage 19 von 20

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Neurotransmitters are released in discrete packages called ( Quanta, Bundles, Quota )

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Frage 20 von 20

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Label the diagram below relating to cells of the cerebellum.

Ziehe eine Antwort zum richtigen orangen Punkt.

Mossy Fibre

Granule Cell

Stellate Cell

Purkinje Cell

Basket Cell

Parallel Fibres

Climbing Fibre

	Erstellt von Matthew Coulson vor fast 6 Jahre

Excitatory and Inhibitory Neurotransmission in the CNS given on 4/9/2018

Physiology III: Excitatory and Inhibitory Neurotransmission in the CNS

Frage 1 von 20

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There is a higher concentration of sodium potassium( sodium, potassium ) on the outside of the cell and potassium sodium( potassium, sodium ) inside the cell

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Frage 2 von 20

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The is a significantly higher lower( higher, lower ) concentration of Calcium extracellularly.

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Frage 4 von 20

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Based on the previous question, will a drug that acts as a Na channel antagonist be excitatory or inhibitory? Inhibitory Excitatory Neither( Inhibitory, Excitatory, Neither )

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Frage 5 von 20

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Based on the previous question, will a drug that acts as a Potassium channel antagonist be excitatory or inhibitory? Excitatory Inhibitory( Excitatory, Inhibitory )

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Frage 6 von 20

Events at the Synapse are mostly mediated by means of ..

Wähle eine der folgenden:

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Frage 7 von 20

There are two types of receptors upon which neurotransmitters can act. ❌: Direct gating, whereby the receptor is an integral part of the channel it controls ❌: Indirect gating, whereby the receptor and the channel it controls are distinct from one another.

Klicke und ziehe, um den Text zu vervollständigen.

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Frage 8 von 20

Label the receptor types shown in the diagram below.

Ziehe eine Antwort zum richtigen orangen Punkt.

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Frage 9 von 20

The major excitatory neurotransmitter is ...

Wähle eine der folgenden:

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Frage 10 von 20

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However, Glutamate can sometimes also elicit inhibitory effects via metabotropic ionotropic( metabotropic, ionotropic ) glutamate receptors

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Frage 11 von 20

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Ionotropic Glutamate Receptors: NMDA receptors mediate slow fast( slow, fast ) excitatory synaptic transmission in the CNS Non-NMDA receptors mediate fast slow( fast, slow ) excitatory synaptic transmission in the CNS

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Frage 12 von 20

The major inhibitory neurotransmitter is ...

Wähle eine der folgenden:

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Frage 13 von 20

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As GABA is an inhibitory Neurotransmitter, it tends to mediate which of the following ions. Potassium & Chlorine Potassium & Sodium Sodium & Chlorine Sodium & Calcium( Potassium & Chlorine, Potassium & Sodium, Sodium & Chlorine, Sodium & Calcium )

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Frage 14 von 20

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Ionotropic GABA receptors tend to mediate Chlorine channels Potassium channels( Chlorine channels, Potassium channels ) Metabotropic GABA receptors tend to mediate Potassium channels Chlorine channels( Potassium channels, Chlorine channels )

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Frage 15 von 20

❌ Receptors are faster and act simply as 'on-off' switches for channels

Klicke und ziehe, um den Text zu vervollständigen.

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Frage 16 von 20

❌): Depolarising change in resting membrane potential caused by actions of neurotransmitters. ❌): Hyperpolarising change change in resting potential caused by actions of neurotransmitters.

Klicke und ziehe, um den Text zu vervollständigen.

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Frage 17 von 20

A change in resting membrane potential caused by EPSP or IPSP that is not of sufficient magnitude to cross the threshold for an action potential is called ...

Wähle eine der folgenden:

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Frage 18 von 20

Fülle die Lücke, um den Text zu vervollständigen

Which neurotransmitter are excitatory neurons most likely to release?

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Frage 19 von 20

Wähle von der Aufklappliste, um den Text zu vervollständigen.

Neurotransmitters are released in discrete packages called Quanta Bundles Quota( Quanta, Bundles, Quota )

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Frage 20 von 20

Label the diagram below relating to cells of the cerebellum.

Ziehe eine Antwort zum richtigen orangen Punkt.

There is a higher concentration of ( sodium, potassium ) on the outside of the cell and ( potassium, sodium ) inside the cell

The is a significantly ( higher, lower ) concentration of Calcium extracellularly.

Based on the previous question, will a drug that acts as a Na channel antagonist be excitatory or inhibitory?
( Inhibitory, Excitatory, Neither )

Based on the previous question, will a drug that acts as a Potassium channel antagonist be excitatory or inhibitory?
( Excitatory, Inhibitory )

There are two types of receptors upon which neurotransmitters can act.
❌: Direct gating, whereby the receptor is an integral part of the channel it controls
❌: Indirect gating, whereby the receptor and the channel it controls are distinct from one another.

However, Glutamate can sometimes also elicit inhibitory effects via ( metabotropic, ionotropic ) glutamate receptors

Ionotropic Glutamate Receptors:
NMDA receptors mediate ( slow, fast ) excitatory synaptic transmission in the CNS
Non-NMDA receptors mediate ( fast, slow ) excitatory synaptic transmission in the CNS

As GABA is an inhibitory Neurotransmitter, it tends to mediate which of the following ions.
( Potassium & Chlorine, Potassium & Sodium, Sodium & Chlorine, Sodium & Calcium )

Ionotropic GABA receptors tend to mediate ( Chlorine channels, Potassium channels )
Metabotropic GABA receptors tend to mediate ( Potassium channels, Chlorine channels )

❌): Depolarising change in resting membrane potential caused by actions of neurotransmitters.
❌): Hyperpolarising change change in resting potential caused by actions of neurotransmitters.

Neurotransmitters are released in discrete packages called ( Quanta, Bundles, Quota )